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Anti-BCL2L1 / BCL-XL Antibody (C-Terminus) IHC-plus™ LS-B451

Note: This antibody replaces LS-C440, LS-C125172
Catalog Size Price
LS-B451-50 50 µg (1 mg/ml) Unavailable

Most Popular BCL2L1 / BCL-XL Antibodies

Anti-BCL2L1 / BCL-XL Antibody (aa46-66) LS-C12146
Rabbit Polyclonal (IgG) to Human BCL2L1 / BCL-XL
Human, Mouse, Rat, Dog, Hamster, Pig
IHC - Paraffin, Western blot
Unconjugated
Anti-BCL2L1 / BCL-XL Antibody (Ser62) IHC-plus™ LS-B1175
Rabbit Polyclonal (IgG) to Human BCL2L1 / BCL-XL
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-BCL2L1 / BCL-XL Antibody LS-C121408
Rabbit Polyclonal (IgG) to Human BCL2L1 / BCL-XL
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Anti-BCL2L1 / BCL-XL Antibody (Internal) LS-C141890
Rabbit Polyclonal to Human BCL2L1 / BCL-XL
Human, Mouse, Rat, Cat, Dog, Hamster, Pig, Rabbit, Sheep
Western blot
Unconjugated
Western blot Image
Anti-BCL2L1 / BCL-XL Antibody (clone 2D1) LS-C174729
Mouse Monoclonal [clone 2D1] (IgG1) to Human BCL2L1 / BCL-XL
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Rabbit Polyclonal to Human BCL2L1 / BCL-XL
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human BCL2L1 / BCL-XL
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ion exchange chromatography
Unmodified

Applications

  • IHC - Paraffin (2.5 µg/ml)
  • Western blot

Specificity and Use

BCL2L1 / BCL-XL antibody was raised against synthetic peptide from human BCL2L1 / Bcl-xL.
LS-E30075 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-B451. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
C-Terminus
peptide corresponding to 14 amino acids near the carboxy-terminus of human Bcl-xL
Immunohistochemistry: LS-B451 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B451 was determined to be 2.5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About BCL2L1 / BCL-XL

Q07817 NM_001191 NP_001182.1

BCL2L1 Antibody, Apoptosis regulator Bcl-X Antibody, Bcl-xL Antibody, BCL-XL/S Antibody, BCLXS Antibody, Bcl-2-like protein 1 Antibody, BCL2-like 1 Antibody, BCL2L Antibody, Bcl-X Antibody, Bcl-xS Antibody, BCLXL Antibody, PPP1R52 Antibody, Bcl2-L-1 Antibody, BCLX Antibody

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane.

Immunohistochemistry

Immunohistochemistry
Anti-BCL2L1 / Bcl-x antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B451 concentration 2.5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-BCL2L1 / Bcl-x antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B451 concentration 5 ug/ml.

Western blot

Western blot
Western blot of Bcl-xL in A549 cell lysates with Bcl-xL antibody at (A) 1 and (B) 2 ug/ml.

Requested From: 
Date Requested: 6/26/2017

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