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BCL2A1

BCL2-related protein A1

BCL2A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: BCL2-related protein A1
Family/Subfamily: Apoptosis
Synonyms: BCL2A1, ACC-1, ACC-2, Bcl-2-like protein 5, Bcl-2-related protein A1, BCL2-related protein A1, BFL1, Bcl2-L-5, BCL2L5, GRS, HBPA1, Protein BFL-1, Protein GRS
Target Sequences: NM_004049 NP_004040.1 Q16548

Publications (1)

1
IL-1 signaling mediates intrauterine inflammation and chorio-decidua neutrophil recruitment and activation. Presicce P, Park CW, Senthamaraikannan P, Bhattacharyya S, Jackson C, Kong F, Rueda CM, DeFranco E, Miller LA, Hildeman DA, Salomonis N, Chougnet CA, Jobe AH, Kallapur SG. JCI insight. 2018 March;3:pii: 98306. [Full Text Article] [PubMed:29563340] [PMC:PMC5926925] Related Antibodies: LS-B450.

☰ Filters
Antibodies (29)
Proteins (9)
ELISA Kits (2)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (4)
Primary (29)
Recombinant (4)
Sandwich (2)
BCL2A1 (40)
Human (29)
Mouse (6)
Rat (6)
Gibbon (3)
Monkey (4)
Pig (3)
IHC (13)
IHC-Fr (2)
IHC-P (6)
WB (25)
Flo (2)
ELISA (14)
IF (4)
IP (2)
Peptide-ELISA (3)
rabbit (25)
mouse (2)
goat (2)
Product Group
IHCPlus (2)
IgG (19)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (27)
OTI3D10 (2)
96-Well Microplate (1)
96-Well Strip Plate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
Carrier-free (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (18)
aa30-65 (7)
C-Terminus (4)
N-Terminus (1)
aa1-16 (1)
aa34-51 (1)
aa45-58 (1)
aa53-81 (1)
aa60-69 (1)
No (39)
Yes (1)
Cell Lysates (1)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
6His, N-terminus (1)
GST (2)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (4)
Human (7)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (3)
Purified (2)
BCL2A1 Antibody - Anti-BCL2A1 antibody IHC of human small intestine, Peyer's patch. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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BCL2A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
BCL2A1 Antibody - Anti-BCL2A1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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BCL2A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
BCL2A1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2A1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2A1.
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BCL2A1 Mouse anti-Human Monoclonal (OTI3D10) Antibody
Human
WB
Unconjugated
100 µl/$450
BCL2A1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY BCL2A1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2A1.
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BCL2A1 Mouse anti-Human Monoclonal (Carrier-free) (OTI3D10) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
BCL2A1 Antibody - A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BCL2A1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
BCL2A1 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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BCL2A1 Rabbit anti-Human Polyclonal (aa30-65) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
BCL2A1 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$902
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BCL2A1 Rabbit anti-Mouse Polyclonal (aa34-51) Antibody
Mouse
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$386
BCL2A1 Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma reacted with BCL2A1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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BCL2A1 Rabbit anti-Human Polyclonal (aa53-81) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
BCL2A1 Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using BCL2A1 Antibody at dilution of 1:100
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BCL2A1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
BCL2A1 Protein
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E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
BCL2A1 Antibody - Western blot analysis of extracts of mouse lung, using BCL2A1 antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
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BCL2A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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BCL2A1 Rabbit anti-Human Polyclonal (aa30-65) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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BCL2A1 Rabbit anti-Human Polyclonal (aa30-65) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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BCL2A1 Rabbit anti-Human Polyclonal (aa30-65) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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BCL2A1 Rabbit anti-Human Polyclonal (aa30-65) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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BCL2A1 Rabbit anti-Human Polyclonal (aa30-65) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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BCL2A1 Rabbit anti-Human Polyclonal (aa30-65) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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BCL2A1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$393
BCL2A1 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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BCL2A1 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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BCL2A1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
0.1 mg/$379
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BCL2A1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
BCL2A1 Antibody - Goat Anti-BCL2A1 Antibody (0.2µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescencence.
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BCL2A1 Goat anti-Human Polyclonal (aa60-69) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
BCL2A1 Antibody - anti-Bcl2A1 antibody, Western blotting All lanes: Anti Bcl2A1 at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ugLane 2: JURKAT Whole Cell Lysate at 40ugPredicted bind size: 30KD Observed bind size: 30KD
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BCL2A1 Rabbit anti-Human Polyclonal (aa1-16) Antibody
Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
BCL2A1 Antibody - BCL2A1 antibody (0.1 ug/ml) staining of Rat Spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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BCL2A1 Goat anti-Rat Polyclonal (aa45-58) Antibody
Rat
Peptide-ELISA, WB
Unconjugated
100 µg/$503
Viewing 1-25 of 40 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).