Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
BCL2A1 Antibody, ACC-1 Antibody, ACC-2 Antibody, Bcl-2-like protein 5 Antibody, Bcl-2-related protein A1 Antibody, BCL2-related protein A1 Antibody, BFL1 Antibody, Bcl2-L-5 Antibody, BCL2L5 Antibody, GRS Antibody, HBPA1 Antibody, Protein BFL-1 Antibody, Protein GRS Antibody
BCL2A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation.
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with BCL2A1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of BCL2A1 Antibody in T47D cell line lysates (35 ug/lane). BCL2A1 (arrow) was detected using the purified antibody.
BCL2A1 Antibody flow cytometry of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.