Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Mouse (tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
IHC - Paraffin (1:1000 - 1:5000)
IHC - Frozen
Western blot (1:1000 - 1:2000)
Immunoprecipitation (1:50 - 1:200)
Specificity and Use
BCL2A1 antibody was raised against a synthetic peptide corresponding to amino acids 34-51 (CRVLQRVAFSVQKEVEKN) of mouse A1, GenBank no. AAH28762.1. Mouse A1 is a 172 aa acid protein. Percent identity with other species by BLAST analysis: Mouse (100%), Rat (94%), Human (89%), Gorilla (89%), Gibbon (89%), Monkey (89%), Hamster (89%), Elephant (89%), Marmoset (83%).
Antiserum, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
BCL2A1 Antibody, ACC-1 Antibody, ACC-2 Antibody, Bcl-2-like protein 5 Antibody, Bcl-2-related protein A1 Antibody, BCL2-related protein A1 Antibody, BFL1 Antibody, Bcl2-L-5 Antibody, BCL2L5 Antibody, GRS Antibody, HBPA1 Antibody, Protein BFL-1 Antibody, Protein GRS Antibody
BCL2A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation.