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Anti-BCL2 / Bcl-2 Antibody (aa61-76, clone G1/G1-4) LS-C189651

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Mouse Monoclonal [clone G1/G1-4] (IgG1,k) to Mouse BCL2 / Bcl-2
Mouse, Rat
Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated

Details

Mouse BCL2 / Bcl-2
Mouse
Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [G1/G1-4]
Affinity purified

Applications

Immunofluorescence (1 - 4 µg/ml), Western blot, Immunoprecipitation

Specificity and Use

BCL2 / Bcl-2 antibody was raised against aa61-76 corresponding to N-terminal region of mouse Bcl-2.
aa61-76
Mouse Bcl-2. Species Crossreactivity: rat.

Packaging

PBS, pH 7.2, 0.09% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months.
For research use only.

About BCL2 / Bcl-2

P10415 NM_000633 NP_000624.2

BCL2 Antibody, Apoptosis regulator Bcl-2 Antibody, B-cell CLL/lymphoma 2 Antibody, B-cell lymphoma protein 2 Antibody, Bcl-2 Antibody, PPP1R50 Antibody

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Requested From: United States
Date Requested: 7/6/2015

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