Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
IHC of paraffin-embedded human breast carcinoma, using BCL-2 (Phospho-Ser70) Antibody. The picture on the right is treated with the synthesized peptide.
Western blot of extracts from HeLa cells treated with LPS (40nM, 30mins), K562 cells treated with calyculin A (50 ng/ml, 30mins) and COS-7 cells treated with H2O2 (1 ng/ml, 15mins), using BCL-2 (Phospho-Ser70) Antibody. The lane on the right is treated with the synthesized peptide.
Requested From: United States
Date Requested: 12/3/2016