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| Catalog Number | Size | Price |
|---|---|---|
| LS-C500256-50 | 50 µg | $294 |
| LS-C500256-100 | 100 µg | $360 |
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Polyclonal Rabbit anti‑Human BCL2 / Bcl‑2 Antibody (IHC, IF) LS‑C500256
Polyclonal Rabbit anti‑Human BCL2 / Bcl‑2 Antibody (IHC, IF) LS‑C500256
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
Bcl-2 antibody LS-C500256 is an unconjugated rabbit polyclonal antibody to human Bcl-2 (BCL2). Validated for ELISA, IF and IHC.
Target
Human BCL2 / Bcl-2
Synonyms
BCL2 | Apoptosis regulator Bcl-2 | B-cell CLL/lymphoma 2 | B-cell lymphoma protein 2 | Bcl-2 | PPP1R50
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Apoptosis regulator Bcl-2 protein (31-80AA)
Specificity
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Applications
- IHC
- Immunofluorescence
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BCL2 / Bcl-2
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Mouse, Rat
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Species:
Human
Applications:
Immunoprecipitation
Species:
Human, Monkey, Dog, Pig
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Species:
Human, Mouse, Rat, Dog
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
