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Anti-BCL2 / Bcl-2 Antibody (clone 8C8, Biotin) LS-C88268

Note: This antibody replaces LS-C35118

Ordering

Wt. Vol. Conc. Price
20 µg 0.1 ml 0.2 mg/ml $320
100 µg 0.5 ml 0.2 mg/ml $635
- 1 ml - $945
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular BCL2 / Bcl-2 Antibodies

Anti-BCL2 / Bcl-2 Antibody (clone E17) LS-C202809
Rabbit Monoclonal [clone E17] (IgG) to Human BCL2 / Bcl-2
Human
IHC - Paraffin, IHC - Frozen
Unconjugated
Anti-BCL2 / Bcl-2 Antibody (C-Terminus) IHC-plus™ LS-B11858
Rabbit Monoclonal (IgG) to Human BCL2 / Bcl-2
Human, Monkey, Mouse, Rat, Bovine
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 8C8] (IgG1) to Human BCL2 / Bcl-2
Human, Monkey, Dog, Pig
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human BCL2 / Bcl-2
Mouse
Human, Monkey, Dog, Pig (tested or 100% immunogen sequence identity)
Bovine (at least 90% immunogen sequence identity)
IgG1 Monoclonal [8C8]
Biotin. Also available Unconjugated.
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (1 - 2 µg/ml)
  • Immunofluorescence
  • Western blot (1 - 2 µg/ml)
  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

BCL2 / Bcl-2 antibody was raised against a Synthetic peptide, aa 41-54 (Cys-GAAPAPGIFSSQPG) of human bcl-2 protein. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Dog, Cat, Pig (100%); Bovine (93%); Horse (86%).
aa 41-54
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

10mM PBS, pH 7.4, with 0.2% BSA and 0.09% Sodium Azide
Stable for 24 months when stored at 2-8°C.
For research use only.

About BCL2 / Bcl-2

P10415 NM_000633 NP_000624.2

BCL2 Antibody, Apoptosis regulator Bcl-2 Antibody, B-cell CLL/lymphoma 2 Antibody, B-cell lymphoma protein 2 Antibody, Bcl-2 Antibody, PPP1R50 Antibody

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Immunohistochemistry

Immunohistochemistry
Formalin-fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and DAB chromogen. Note absence of staining of reactive cells in the germinal center. This image was taken for the unmodified form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/4/2016

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