Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Human BCL10 / BCL-10
Human, Mouse (tested or 100% immunogen sequence identity)
IHC - Paraffin (1:200 - 1:1000)
Immunofluorescence (1:200 - 1:800)
Western blot (1:500 - 1:2000)
Specificity and Use
BCL10 / BCL-10 antibody was raised against purified recombinant fragment of human BCL-10 expressed in E. coli.
Recognizes human BCL-10 at 26kD. Species cross-reactivity: mouse.
Suitable for use in ELISA, Western Blot., Immunofluorescence and Immunohistochemistry. ELISA: 1:10000. Western Blot: 1:500-1:2000. Immunofluorescence: 1:200-1:800. Immunohistochemistry (Paraffin): 1:200-1:1000.
0.04% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months
Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP. Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene.