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BCL10 / BCL-10
B-cell CLL/lymphoma 10
Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP. Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene. Overexpression of Bcl10 induces JNK, p38, and NF-kB activation. Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing and induces apoptosis through caspase-9 activation. Bcl10 exhibits a variety of mutations in MALT lymphomas and in B and T cell lineage lymphomas indicating that it may be commonly involved in the pathogenesis of human malignancy. Bcl10 is expressed in many human and murine tissues and cell lines.
| Gene Name: | B-cell CLL/lymphoma 10 |
| Family/Subfamily: | Apoptosis |
| Synonyms: | BCL10, Bcl-10, B-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, CARMEN, CARD-like apoptotic protein, CCARMEN, C-E10, CIPER, Cellular-E10, HCLAP, Cellular homolog of vCARMEN, CLAP, ME10 |
| Target Sequences: | NM_003921 NP_003912.1 O95999 |
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BCL10 / BCL-10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
BCL10 / BCL-10 Mouse anti-Human Monoclonal Antibody
Mouse, Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
BCL10 / BCL-10 Mouse anti-Human Monoclonal (aa122-168) (BL10/411) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
BCL10 / BCL-10 Mouse anti-Human Monoclonal (aa122-168) (Ready-to-Use) (BL10/411) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7 ml/$574
BCL10 / BCL-10 Mouse anti-Human Monoclonal (aa122-168) (Azide-free, BSA-free) (BL10/411) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (aa24-51) Antibody
Mouse, Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (aa24-51) (Biotin) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (aa24-51) (FITC) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (aa24-51) (APC) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (aa24-51) (PE) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (aa24-51) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Cancer
BCL10 / BCL-10 Mouse anti-Human Monoclonal (151) Antibody
Human
ELISA, Flo, IHC-P, IP, WB
Unconjugated
0.05 mg/$440
Cancer
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (aa5-19) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$545
E. coli
His-SUMO
42.2 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
BCL10 / BCL-10 Mouse anti-Human Monoclonal (OTI6A8) Antibody
Dog, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
BCL10 / BCL-10 Mouse anti-Human Monoclonal (OTI4A8) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
BCL10 / BCL-10 Mouse anti-Human Monoclonal (Carrier-free) (OTI4A8) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Cancer
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (aa111-160) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
BCL10 / BCL-10 Rabbit anti-Human Polyclonal (aa24-51) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
BCL10 / BCL-10 Mouse anti-Human Monoclonal (aa122-168) (SPM520) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
BCL10 / BCL-10 Mouse anti-Human Monoclonal (aa122-168) (Azide-free, BSA-free) (SPM520) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
BCL10 / BCL-10 Mouse anti-Human Monoclonal (aa1-143) (1185CT13.2.1.2) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
BCL10 / BCL-10 Mouse anti-Human Monoclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$649
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