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Anti-BCL10 / BCL-10 Antibody (aa122-168, clone 151) LS-C95617

Ordering

Wt. Vol. Conc. Price
- 0.5 ml - $305
- 1 ml - $405
Inquire for larger quantities

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Most Popular BCL10 / BCL-10 Antibodies

Anti-BCL10 / BCL-10 Antibody (aa122-168) LS-C74728
Mouse Monoclonal (IgG1) to Human BCL10 / BCL-10
Human
IHC, Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 151] (IgG1) to Human BCL10 / BCL-10
Human
Unconjugated

Details

Human BCL10 / BCL-10
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [151]
Unconjugated
Protein G purified
Unmodified

Specificity and Use

BCL10 / BCL-10 antibody was raised against human recombinant Bcl-10.
aa122-168
Monoclonal Anti-Bcl-10 reacts specifically with human Bcl-10. The epitope recognized by the antibody resides within amino acids 122-168 of human Bcl-10 molecule. Bcl-10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl-10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl-10 cellular overexpression induces JNK, p38, and NF-kB activation. Deregulation of Bcl-10 expression is also demonstrated to be involved in cellular oncogenesis.

Packaging

0.05% sodium azide
Store at 2°C to 8°C degrees. Do not freeze.
For research use only.

About BCL10 / BCL-10

O95999 NM_003921 NP_003912.1

BCL10 Antibody, Bcl-10 Antibody, B-cell CLL/lymphoma 10 Antibody, B-cell lymphoma/leukemia 10 Antibody, CARMEN Antibody, CARD-like apoptotic protein Antibody, CCARMEN Antibody, C-E10 Antibody, CIPER Antibody, Cellular-E10 Antibody, HCLAP Antibody, Cellular homolog of vCARMEN Antibody, CLAP Antibody, ME10 Antibody

Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP. Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene.

Requested From: United States
Date Requested: 12/4/2016

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