BCCIP

BRCA2 and CDKN1A interacting protein

BCCIP was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

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Products

Antibodies (12)

Proteins (10)

Type

Over-Expression Lysate (6)

Primary (12)

Recombinant (4)

Target

BCCIP (22)

Reactivity

Human (12)

Mouse (2)

Rat (2)

Application

IHC (6)

IHC-P (1)

WB (10)

ELISA (2)

ICC (1)

IF (3)

IP (2)

Peptide-ELISA (1)

Host

rabbit (10)

mouse (2)

Isotype

IgG (9)

IgG2b (1)

Clonality

monoclonal mc (1)

polyclonal pc (11)

Format

Unconjugated (12)

Epitope

60-140 aa, Internal (1)

C-Terminus (1)

aa1-50 (1)

aa181-273 (1)

aa250-C-term (1)

aa300-350 (1)

Publications

No (22)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (7)

Species

Human (7)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (2)

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BCCIP Antibody (aa181-273) LS-C186295

Antibody:

BCCIP Rabbit anti-Human Polyclonal (aa181-273) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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BCCIP Antibody (aa300-350) LS-C286842

Antibody:

BCCIP Rabbit anti-Human Polyclonal (aa300-350) Antibody

Reactivity:

Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

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BCCIP Antibody LS-C660094

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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BCCIP Antibody LS-C410121

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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BCCIP Antibody LS-C807819

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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BCCIP Antibody LS-C764817

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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BCCIP Antibody (60-140 aa, Internal) LS-C386456

Antibody:

BCCIP Rabbit anti-Human Polyclonal (60-140 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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BCCIP Antibody (aa250-C-term) LS-C288949

Antibody:

BCCIP Rabbit anti-Human Polyclonal (aa250-C-term) Antibody

Reactivity:

Human

Applications:

IHC, IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

Select

BCCIP Antibody LS-C306519

Antibody:

BCCIP Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

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BCCIP Antibody (aa1-50) LS-C288948

Antibody:

BCCIP Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

BCCIP Antibody (C-Terminus) LS-C125207

Antibody:

BCCIP Mouse anti-Human Monoclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

Select

BCCIP Antibody LS-C668769

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

Human BCCIP Protein (Recombinant GST) (Full Length) - LS-G34561

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

60.17 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human BCCIP Protein (Recombinant GST, N-terminus) (aa210-314) - LS-G62848

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human BCCIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90464

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36 kDa

Price:

20 µg/$150

Select

Human BCCIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90465

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.8 kDa

Price:

20 µg/$150

Select

Human BCCIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90466

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

20 µg/$150

Select

BCCIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107919

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.8 kDa

Price:

100 µg/$494

Select

BCCIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107918

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

100 µg/$494

Select

BCCIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112515

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36 kDa

Price:

100 µg/$494

Select

Human BCCIP Protein (Recombinant His) - LS-G2962

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

Select

Human BCCIP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71720

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.8 kDa

Price:

20 µg/$1,107

Viewing 1-22 of 22 product results

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