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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BCAR1 / p130Cas Antibody (aa66‑412) LS‑C126105
Antibody
P130Cas antibody LS-C126105 is an unconjugated sheep polyclonal antibody to p130Cas (BCAR1) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C126105-100
100 µg
Unavailable

Popular BCAR1 / p130Cas Products

Antibody
Species: Human, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Anti-BCAR1 / p130Cas antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8632 dilution 10 ug/ml.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
IHC of paraffin-embedded human breast carcinoma, using p130 Cas (Phospho-Tyr165) Antibody. The sample on the right was incubated with synthetic peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-BCAR1 / p130Cas antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11057 dilution 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-BCAR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Species: Human, Monkey, Mouse, Rat, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry

Product Description

P130Cas antibody LS-C126105 is an unconjugated sheep polyclonal antibody to p130Cas (BCAR1) from human, mouse and rat. Validated for WB.
About BCAR1 / p130Cas
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells. P56945 NM_014567 NP_055382.2

BCAR1 Antibody, CAS Antibody, CAS1 Antibody, CRKAS Antibody, CASS1 Antibody, CRK-associated substrate Antibody, p130Cas Antibody


Specifications

Target
Human BCAR1 / p130Cas
Host
Sheep
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 µg/ml)
Immunogen
BCAR1 / p130Cas antibody was raised against e. coli-derived recombinant human p130Cas (aa66-412).
Epitope
aa66-412
Specificity
Recognizes endogenous human p130Cas at 105-130kD. Species cross-reactivity: mouse, rat.
Usage
Suitable for use in Western blot: 1 ug/ml.
Presentation
Lyophilized from 0.2 um filtered solution in PBS, 5% trehalose
Reconstitution
Sterile PBS, sterile 40-50% glycerol, 0.02% sodium azide.
Storage
Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Reconstituted product is stable for 1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/17/2018

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