BBS7

Bardet-Biedl syndrome 7

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.

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Products

Antibodies (27)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (27)

Recombinant (3)

Target

BBS7 (32)

Reactivity

Human (27)

Mouse (8)

Rat (1)

Application

IHC (2)

IHC-P (1)

WB (21)

ELISA (15)

IF (4)

Peptide-ELISA (1)

Host

rabbit (21)

mouse (6)

Product Group

IHCPlus (1)

Isotype

IgG (20)

IgG2a,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (21)

Format

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (3)

Unconjugated (9)

Epitope

aa73-99 (7)

aa263-540 (1)

aa574-673 (1)

Publications

No (32)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ BBS7 Antibody (aa263-540) LS-B14804

(4.0) Rating

Antibody:

BBS7 Rabbit anti-Human Polyclonal (aa263-540) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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BBS7 Antibody LS-C808894

Antibody:

BBS7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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BBS7 Antibody LS-C659821

Antibody:

BBS7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

100 µg/$341

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BBS7 Antibody LS-C659823

Antibody:

BBS7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

100 µg/$331

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BBS7 Antibody LS-C673903

Antibody:

BBS7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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BBS7 Antibody (HRP) LS-C673905

Antibody:

BBS7 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP

• Unconjugated
• HRP

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BBS7 Antibody (aa574-673) LS-C306510

Antibody:

BBS7 Mouse anti-Human Monoclonal (aa574-673) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

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BBS7 Antibody (HRP) LS-C541064

Antibody:

BBS7 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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BBS7 Antibody (Biotin) LS-C520932

Antibody:

BBS7 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

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BBS7 Antibody (FITC) LS-C530976

Antibody:

BBS7 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

BBS7 Antibody (PE) LS-C649175

Antibody:

BBS7 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

Select

BBS7 Antibody (APC) LS-C512717

Antibody:

BBS7 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

BBS7 Antibody (aa73-99) LS-C319787

Antibody:

BBS7 Rabbit anti-Human Polyclonal (aa73-99) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

BBS7 Antibody (aa73-99, Biotin) LS-C233075

Antibody:

BBS7 Rabbit anti-Human Polyclonal (aa73-99) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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BBS7 Antibody (aa73-99, FITC) LS-C233076

Antibody:

BBS7 Rabbit anti-Human Polyclonal (aa73-99) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

BBS7 Antibody (aa73-99, APC) LS-C233074

Antibody:

BBS7 Rabbit anti-Human Polyclonal (aa73-99) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

BBS7 Antibody (aa73-99, PE) LS-C233077

Antibody:

BBS7 Rabbit anti-Human Polyclonal (aa73-99) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

BBS7 Antibody (aa73-99, Azide-free, HRP) LS-C249507

Antibody:

BBS7 Rabbit anti-Human Polyclonal (aa73-99) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

BBS7 Antibody LS-C309589

Antibody:

BBS7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

BBS7 Antibody (HRP) LS-C541062

Antibody:

BBS7 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

BBS7 Antibody (Biotin) LS-C520931

Antibody:

BBS7 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

BBS7 Antibody (FITC) LS-C530975

Antibody:

BBS7 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

Select

BBS7 Antibody (PE) LS-C649174

Antibody:

BBS7 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

Select

BBS7 Antibody (APC) LS-C512716

Antibody:

BBS7 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

BBS7 Antibody (aa73-99) LS-C159168

Antibody:

BBS7 Rabbit anti-Human Polyclonal (aa73-99) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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