BBS4

Bardet-Biedl syndrome 4

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. Required for microtubule anchoring at the centrosome but not for microtubule nucleation. May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome.

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Products

Antibodies (25)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (25)

Recombinant (2)

Target

BBS4 (29)

Reactivity

Human (25)

Mouse (17)

Rat (8)

Bat (6)

Bovine (3)

Chimpanzee (6)

Dog (7)

Gibbon (6)

Horse (7)

Monkey (8)

Pig (4)

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Zebrafish (3)

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IHC (2)

IHC-P (1)

WB (24)

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IP (1)

Peptide-ELISA (3)

Host

rabbit (19)

mouse (4)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (11)

IgG1 (3)

Clonality

monoclonal mc (3)

polyclonal pc (22)

Clone

1292CT845.130.218 (1)

OTI2D5 (2)

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APC Conjugated (1)

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aa215-264 (4)

aa71-120 (4)

aa266-519 (2)

aa1-240 (1)

aa125-139 (1)

aa33-46 (1)

aa337-369 (1)

aa350-519 (1)

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HEK 293 Cells (2)

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IHC-plus™ BBS4 Antibody (aa350-519) LS-B15245

(4.0) Rating

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa350-519) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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BBS4 Antibody (aa1-240, clone 1292CT845.130.218) LS-C344122

Antibody:

BBS4 Mouse anti-Human Monoclonal (aa1-240) (1292CT845.130.218) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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BBS4 Antibody LS-C802851

Antibody:

BBS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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BBS4 Antibody LS-C309586

Antibody:

BBS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$749

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BBS4 Antibody LS-C834214

Antibody:

BBS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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BBS4 Antibody (aa33-46) LS-C139721

Antibody:

BBS4 Goat anti-Human Polyclonal (aa33-46) Antibody

Reactivity:

Rabbit, Mouse, Dog, Pig, Horse, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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BBS4 Antibody (aa125-139) LS-C139722

Antibody:

BBS4 Goat anti-Human Polyclonal (aa125-139) Antibody

Reactivity:

Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

BBS4 Antibody (aa266-519, clone OTI2D5) LS-C339228

Antibody:

BBS4 Mouse anti-Human Monoclonal (aa266-519) (OTI2D5) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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BBS4 Antibody (aa266-519, clone OTI2D5, Carrier-free) LS-C790309

Antibody:

BBS4 Mouse anti-Human Monoclonal (aa266-519) (Carrier-free) (OTI2D5) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

BBS4 Antibody LS-C309588

Antibody:

BBS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

BBS4 Antibody (HRP) LS-C541063

Antibody:

BBS4 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

BBS4 Antibody (Biotin) LS-C520930

Antibody:

BBS4 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

BBS4 Antibody (FITC) LS-C530974

Antibody:

BBS4 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

Select

BBS4 Antibody (APC) LS-C512715

Antibody:

BBS4 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

Select

BBS4 Antibody (PE) LS-C649176

Antibody:

BBS4 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

BBS4 Antibody (aa215-264) LS-C116738

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa215-264) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

BBS4 Antibody (aa215-264, HRP) LS-C463914

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa215-264) (HRP) Antibody

Reactivity:

Zebrafish, Horse, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

BBS4 Antibody (aa215-264, Biotin) LS-C463912

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa215-264) (Biotin) Antibody

Reactivity:

Zebrafish, Horse, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

BBS4 Antibody (aa215-264, FITC) LS-C463913

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa215-264) (FITC) Antibody

Reactivity:

Zebrafish, Horse, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BBS4 Antibody (aa71-120) LS-C116737

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa71-120) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

BBS4 Antibody (aa71-120, HRP) LS-C463911

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody

Reactivity:

Mouse, Dog, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

BBS4 Antibody (aa71-120, Biotin) LS-C463909

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody

Reactivity:

Mouse, Dog, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

BBS4 Antibody (aa71-120, FITC) LS-C463910

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody

Reactivity:

Mouse, Dog, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BBS4 Antibody (aa337-369) LS-C100183

Antibody:

BBS4 Rabbit anti-Human Polyclonal (aa337-369) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

BBS4 Antibody LS-C306508

Antibody:

BBS4 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

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