Human, Orangutan, Monkey, Dog, Pig
(tested or 100% immunogen sequence identity)
Bat (at least 90% immunogen sequence identity)
Protein G purified
Also available Unmodified
- IHC - Paraffin (0.5 - 1 µg/ml)
- Immunofluorescence (1 - 2 µg/ml)
- Western blot (0.5 - 1 µg/ml)
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
- (applications tested for the base form of this product only)
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BAX antibody was raised against amino acids GSGEQPRGGGPTSS (3-16) were used as the immunogen for this anti-human Bax antibody. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Baboon, Monkey, Ferret, Cat, Pig, Dog (100%); Bat, Elephant (93%).
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a protein of 21kDa, identified as the Bax protein. The Bax antibody is highly specific and shows no cross-reaction with Bcl-2 alpha or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and the protein also counters the death repressor activity of Bcl-2. ELISA: Order BSA-free format for coating.
Store at 2°C to 8°C.
For research use only.
This antibody carries the LSBio 100% Guarantee.