Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
BAX, BCL2-associated X protein, Bcl2-L-4, Apoptosis regulator BAX, Bcl-2-like protein 4, BCL2L4
(tested or 100% immunogen sequence identity)
IHC (1:500 - 1:2000)
Western blot (1:500 - 1:2000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
BAX antibody was raised against synthetic peptide corresponding to aa 43-61 (P43ELTLEQPPQDASTKKLSE61) of mouse Bax. This sequence is completely conserved in rat Bax. Percent identity by BLAST analysis: Mouse, Rat (100%); Sheep, Hamster, Panda, Bovine, Dog, Cat, Pig (89%); Horse (84%).
Recognizes human, mouse and rat Bax.
Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry. Western Blot: 1:500-1:2000. Immunohistochemistry: 1:500-1:2000. Immunoprecipitation: 1 ul/1E6 cells.
PBS, 0.05% Sodium Azide
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.