BATF

basic leucine zipper transcription factor, ATF-like

AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system: specifically mediates the differentiation of T-helper 17 cells (Th17), follicular T-helper cells (TfH), CD8+ dendritic cells and class-switch recombination (CSR) in B-cells. Acts via the formation of a heterodimer with JUNB that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3'. The BATF-JUNB heterodimer also forms a complex with IRF4 (or IRF8) in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 (or IRF8) and activation of genes. Controls differentiation of T-helper cells producing interleukin-17 (Th17 cells) by binding to Th17-associated gene promoters: regulates expression of the transcription factor RORC itself and RORC target genes such as IL17 (IL17A or IL17B). Also involved in differentiation of follicular T-helper cells (TfH) by directing expression of BCL6 and MAF. In B-cells, involved in class-switch recombination (CSR) by controlling the expression of both AICDA and of germline transcripts of the intervening heavy-chain region and constant heavy-chain region (I(H)-C(H)). Following infection, can participate in CD8+ dendritic cell differentiation via interaction with IRF4 and IRF8 to mediate cooperative gene activation. Regulates effector CD8+ T-cell differentiation by regulating expression of SIRT1. Following DNA damage, part of a differentiation checkpoint that limits self-renewal of hematopoietic stem cells (HSCs): up-regulated by STAT3, leading to differentiation of HSCs, thereby restricting self-renewal of HSCs.

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Products

Antibodies (46)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (46)

Recombinant (4)

Target

BATF (52)

Reactivity

Human (46)

Mouse (18)

Rat (14)

Bat (3)

Bovine (3)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (6)

Rabbit (3)

Zebrafish (3)

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Application

IHC (12)

IHC-P (3)

WB (39)

ELISA (23)

IF (2)

IP (6)

Peptide-ELISA (3)

Host

rabbit (37)

mouse (8)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (34)

IgG1 (1)

IgG1,k (6)

Clonality

monoclonal mc (7)

polyclonal pc (39)

Clone

7C8F3 (1)

Format

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (6)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (3)

Unconjugated (22)

Epitope

aa7-35 (7)

N-Terminus (5)

aa35-84 (4)

10-90 aa, N-terminal (1)

aa10-59 (1)

aa105-119 (1)

aa34-125 (1)

Publications

No (52)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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IHC-plus™ BATF Antibody (aa7-35) LS-B15665

(4.0) Rating

Antibody:

BATF Rabbit anti-Human Polyclonal (aa7-35) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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BATF Antibody (aa35-84) LS-C101409

Antibody:

BATF Rabbit anti-Human Polyclonal (aa35-84) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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BATF Antibody LS-C153723

Antibody:

BATF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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BATF Antibody LS-C377460

Antibody:

BATF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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BATF Antibody (HRP) LS-C377462

Antibody:

BATF Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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BATF Antibody (Biotin) LS-C377464

Antibody:

BATF Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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BATF Antibody (FITC) LS-C377461

Antibody:

BATF Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BATF Antibody LS-C659711

Antibody:

BATF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$331

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BATF Antibody (aa34-125) LS-C306503

Antibody:

BATF Mouse anti-Human Monoclonal (aa34-125) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$705

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BATF Antibody (HRP) LS-C541059

Antibody:

BATF Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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BATF Antibody (Biotin) LS-C520926

Antibody:

BATF Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

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BATF Antibody (FITC) LS-C530972

Antibody:

BATF Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$904

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BATF Antibody (APC) LS-C512712

Antibody:

BATF Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IP, WB

Format:

APC Conjugated

Price:

100 µl/$904

Select

BATF Antibody (PE) LS-C649173

Antibody:

BATF Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IP, WB

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

BATF Antibody LS-C800630

Antibody:

BATF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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BATF Antibody (10-90 aa, N-terminal) LS-C382246

Antibody:

BATF Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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BATF Antibody (aa10-59) LS-C119079

Antibody:

BATF Rabbit anti-Human Polyclonal (aa10-59) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

BATF Antibody LS-C822970

Antibody:

BATF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$357

Select

BATF Antibody (clone 7C8F3) LS-C682546

Antibody:

BATF Mouse anti-Human Monoclonal (7C8F3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

BATF Antibody LS-C831909

Antibody:

BATF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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BATF Antibody LS-C830416

Antibody:

BATF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

BATF Antibody (aa7-35) LS-C319782

Antibody:

BATF Rabbit anti-Human Polyclonal (aa7-35) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

BATF Antibody (aa7-35, FITC) LS-C252395

Antibody:

BATF Rabbit anti-Human Polyclonal (aa7-35) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

BATF Antibody (aa7-35, PE) LS-C252397

Antibody:

BATF Rabbit anti-Human Polyclonal (aa7-35) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• FITC
• PE

• Unconjugated
• FITC
• PE

Select

BATF Antibody LS-C416287

Antibody:

BATF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Viewing 1-25 of 52 product results

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