Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse (tested or 100% immunogen sequence identity)
Western blot (1 - 2 µg/ml)
Specificity and Use
BAK1 / BAK antibody was raised against a peptide corresponding to 13 amino acids near the amino-terminus of human Bak.
Species cross-reactivity: Human and Mouse.
Suitable for use in Western blot: 1-2 ug/ml.
PBS, 0.02% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C.
BAK1 Antibody, Apoptosis regulator BAK Antibody, BAK Antibody, BCL2L7 Antibody, Bcl-2-like protein 7 Antibody, BCL2-antagonist/killer 1 Antibody, Bcl2-L-7 Antibody, BCL2-like 7 protein Antibody, CDN1 Antibody, Pro-apoptotic protein BAK Antibody, BAK-LIKE Antibody
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria.