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BAK1 / BAK

BCL2-antagonist/killer 1

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria. It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability.

Gene Name: BCL2-antagonist/killer 1
Synonyms: BAK1, Apoptosis regulator BAK, BAK, BCL2L7, Bcl-2-like protein 7, BCL2-antagonist/killer 1, Bcl2-L-7, BCL2-like 7 protein, CDN1, Pro-apoptotic protein BAK, BAK-LIKE
Target Sequences: NM_001188 NP_001179.1 Q16611

Publications (1)

1
Dissociation of Bak a1 helix from the core and latch domains is required for apoptosis. Alsop AE, Fennell SC, Bartolo RC, Tan IK, Dewson G, Kluck RM. Nature communications. 2015 6:6841. (IHC; Human) [Full Text Article] [PubMed:25880232] Related Antibodies: LS-C12099.

☰ Filters
Antibodies (60)
ELISA Kits (15)
Proteins (6)
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Custom (1)
Over-Expression Cell Culture Supernatant (1)
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Primary (60)
Recombinant (2)
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Sandwich CLIA (1)
BAK1 / BAK (81)
Human (67)
Mouse (29)
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IHC (32)
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rabbit (55)
mouse (3)
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monoclonal mc (4)
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aa56-91 (7)
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BAK1 / BAK Rabbit anti-Human Polyclonal (aa2-14) Antibody
Human, Monkey
IF, IHC, IP, WB
Unconjugated
50 µg/$577; 200 µg/$1,001
BAK1 / BAK ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
BAK1 / BAK ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
BAK1 / BAK Antibody - Anti-BAK1 / BAK antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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BAK1 / BAK Rabbit anti-Human Polyclonal Antibody
Hamster, Pig, Human, Monkey
IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$535
BAK1 / BAK Antibody - Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using BAK1 mouse mAb with DAB staining.
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BAK1 / BAK Mouse anti-Human Monoclonal (2H9H7) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
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BAK1 / BAK Rabbit anti-Human Monoclonal Antibody
Human
Flo, IF, IHC, IP, WB
Unconjugated
20 µl/$299; 50 µl/$341; 100 µl/$431; 200 µl/$539
BAK1 / BAK Antibody - BAK antibody IHC-paraffin. IHC(P): Mouse Skeletal Muscle Tissue.
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BAK1 / BAK Rabbit anti-Human Polyclonal (aa22-211) Antibody
Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
BAK1 / BAK Antibody - Anti-BAK1 / BAK antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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BAK1 / BAK Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Hamster, Human
IHC, IHC-P
Unconjugated
250 µl/$460
BAK1 / BAK Antibody - Immunohistochemistry of paraffin-embedded human kidney cancer tissue.
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BAK1 / BAK Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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BAK1 / BAK Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, IP, WB
Biotin Conjugated
100 µl/$1,119
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BAK1 / BAK Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, ICC, IF, WB
Unconjugated
50 µl/$303; 100 µl/$365
BAK1 / BAK Antibody - Anti-BAK1 / BAK antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
BAK1 / BAK Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
BAK1 / BAK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
BAK1 / BAK Antibody - 1:200 staining human skeletal muscle tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BAK1 / BAK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
BAK1 / BAK Antibody - Western blot of Bak antibody
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BAK1 / BAK Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
BAK1 / BAK Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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BAK1 / BAK Rabbit anti-Human Polyclonal (aa56-91) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
BAK1 / BAK Antibody - IHC of Bak (A2) pAb in paraffin-embedded human skeletal muscle tissue.
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BAK1 / BAK Rabbit anti-Human Polyclonal (Ala2) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
BAK1 / BAK Antibody - BAK1 / BAK antibody. IHC(P): Rat Lung Tissue.
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BAK1 / BAK Rabbit anti-Human Polyclonal (aa74-95) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
BAK1 / BAK ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.156 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Select
HEK 293 Cells
8His, N-terminus
22.9 kDa
100 µg/$298
BAK1 / BAK Antibody
Select
BAK1 / BAK Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
BAK1 / BAK Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using BAK1 Polyclonal Antibody at dilution of 1:50.
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BAK1 / BAK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
BAK1 / BAK Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
BAK1 / BAK Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
BAK1 / BAK Rabbit anti-Human Polyclonal (aa56-91) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
BAK1 / BAK Rabbit anti-Human Polyclonal (aa56-91) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Viewing 1-25 of 81 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).