Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone Buffy-1] (IgG2a) to Human BAFF
ICC, Western blot, Flow Cytometry (applications tested for the base form of this product only)
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [Buffy-1]
(applications tested for the base form of this product only)
Specificity and Use
BAFF antibody was raised against recombinant human soluble BAFF (aa. 83-285). Anti BAFF (monoclonal Buffy-1) antibody was purified to greater than or equal to 95% in SDS-PAGE and is supplied at a concentration of 0.1 mg/1ml.
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-kB and c-jun N-terminal Kinase).