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Anti-BACE2 Antibody (C-Terminus) IHC-plus™ LS-B3764

Note: This antibody replaces LS-C376

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml Unavailable

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Rabbit Polyclonal to Human BACE2
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human BACE2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.5 - 1 µg/ml)

Specificity and Use

BACE2 antibody was raised against synthetic peptide from human BACE2.
LS-E29927 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-B3764. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
C-Terminus
peptide corresponding to amino acids near the carboxy terminus of human BACE2

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About BACE2

Q9Y5Z0 NM_012105 NP_036237.2

BACE2 Antibody, 56 kDa aspartic-like protease Antibody, AEPLC Antibody, ALP56 Antibody, Aspartic-like protease 56 kDa Antibody, APL56 Antibody, BAE2 Antibody, Beta-secretase 2 Antibody, ASP21 Antibody, CDA13 Antibody, DRAP Antibody, Memapsin-1 Antibody, Asp 1 Antibody, ASP1 Antibody, Aspartyl protease 1 Antibody, Theta-secretase Antibody, Beta secretase 2 Antibody, CEAP1 Antibody, Down region aspartic protease Antibody

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.

Immunohistochemistry

Immunohistochemistry
Anti-BACE2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3764 concentration 5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-BACE2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3764 concentration 5 ug/ml.

Western blot

Western blot
Western blot of BACE2 in human heart tissue lysate in the absence (A) or presence (B) of blocking peptide with BACE2 antibody at 1 ug/ml.

Requested From: 
Date Requested: 4/25/2017

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