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Anti-B2M / Beta 2 Microglobulin Antibody (clone 2213) IHC-plus™ LS-B2249

Note: This antibody replaces LS-C11402


Wt. Vol. Conc. Price
- 50 µl 1.1 mg/ml $395

LSBio (Direct) LSBio (Direct)

Other B2M / Beta 2 Microglobulin Products

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Mouse Monoclonal [clone 2213] (IgG1) to Human B2M / Beta 2 Microglobulin
IHC - Paraffin, ELISA


Human B2M / Beta 2 Microglobulin
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2213]
Protein A purified


IHC - Paraffin (5 µg/ml), ELISA

Specificity and Use

B2M / Beta 2 Microglobulin antibody was raised against highly pure beta-2-microglobulin from human urine.
Specific for human beta 2 microglobulin. B2M is the beta chain of MHC class I molecules. The precursor protein has a molecular weight of approximately 14 kD and is 119 amino acids in length.
Immunohistochemistry: LS-B2249 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2249 was determined to be 5 ug/ml.


PBS, pH 8.0, 0.05% sodium azide, 10% glycerol.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About B2M / Beta 2 Microglobulin

P61769 NM_004048 NP_004039.1

B2M Antibody, Beta 2 Microglobulin Antibody, Beta-2-microglobulin Antibody, Beta-2-microglobin Antibody

B2M / Beta 2 Microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.


Anti-B2M antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2249 concentration 5 ug/ml.


Anti-B2M antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2249 concentration 5 ug/ml.

Requested From: United States
Date Requested: 11/25/2015

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