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Anti-AXIN1 / Axin-1 Antibody (Internal) LS-C20825

Catalog Size Price
LS-C20825-100 100 µg (0.25 mg/ml) Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human AXIN1 / Axin-1
Western blot (applications tested for the base form of this product only)


Human AXIN1 / Axin-1
Human (tested or 100% immunogen sequence identity)
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Immunoaffinity purified


  • Western blot (0.1 - 2 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

AXIN1 / Axin-1 antibody was raised against synthetic peptide derived from the internal region of the human Axin protein. Based on amino acid sequence, this antibody is not expected to cross-react with Axin-2.
Reacts with the human Axin protein. On Western blots, it recognizes a doublet band at ~120-130kD. The sequence used for this antibody shares 86% sequence homology with mouse, rat, and chicken Axin. Reactivity is confirmed with human Jurkat leukemia T cell lysates.
Suitable for use in Western Blot. Western Blot: 0.1-2.0 ug/ml.


PBS, pH 7.4, 0.1% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About AXIN1 / Axin-1

O15169 AF009674 AAC51624.1

AXIN1 Antibody, Axis inhibitor 1 Antibody, AXIN Antibody, Axin 1 Antibody, Axis inhibition protein 1 Antibody, Fused, mouse, homolog of Antibody, HAxin Antibody, PPP1R49 Antibody, Axin-1 Antibody

Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B.

Requested From: 
Date Requested: 2/21/2018

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