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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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AURKC / Aurora C Antibody (aa115‑145) LS‑C98896
Aurora C antibody LS-C98896 is an unconjugated rabbit polyclonal antibody to human Aurora C (AURKC). Validated for IF and WB.
Catalog
Size
Price
LS-C98896-400
400 µl
Unavailable

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Product Description

Aurora C antibody LS-C98896 is an unconjugated rabbit polyclonal antibody to human Aurora C (AURKC). Validated for IF and WB.
About AURKC / Aurora C
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Q9UQB9 NM_003160 NP_003151.2

AURKC Antibody, AIE2 Antibody, Aie1 Antibody, AIRK3 Antibody, ARK-3 Antibody, Aurora kinase C Antibody, Aurora-related kinase 3 Antibody, AurC Antibody, Aurora 3 Antibody, Aurora C Antibody, Aurora/IPL1-related kinase 3 Antibody, ARK3 Antibody, Aurora-C Antibody, AIK3 Antibody, HsAIRK3 Antibody, SPGF5 Antibody, Aurora/IPL1/Eg2 protein 2 Antibody, STK13 Antibody


Specifications

Target
Human AURKC / Aurora C
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Immunofluorescence (1:100 - 1:500)
  • Western blot (1:1000)
Blocking Peptide
LS-E8596 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C98896. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa115-145
Specificity
This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-145 amino acids from the Central region of human Aurora-C.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Aurora-C Antibody (Ctr) western blot of 293 cell line lysates (35 ug/lane). The Aurora-C antibody detected the Aurora-C protein (arrow).
Aurora-C Antibody (Ctr) western blot of 293 cell line lysates (35 ug/lane). The Aurora-C antibody detected the Aurora-C protein (arrow).

Western blot

The anti-Aurora C antibody is used in Western blot to detect Aurora C in lysates of 293 cells expressing Flag tag (lane 1), Flag-tagged Aurora A (lane 2), Flag-tagged Aurora B (lane 3), and Flag-tagged Aurora C (lane 4). Data is kindly provided by Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).
The anti-Aurora C antibody is used in Western blot to detect Aurora C in lysates of 293 cells expressing Flag tag (lane 1), Flag-tagged Aurora A (lane 2), Flag-tagged Aurora B (lane 3), and Flag-tagged Aurora C (lane 4). Data is kindly provided by Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).

Western blot

Aurora-C Antibody (Ctr) western blot of 293 cell line lysates (35 ug/lane). The Aurora-C antibody detected the Aurora-C protein (arrow).
Aurora-C Antibody (Ctr) western blot of 293 cell line lysates (35 ug/lane). The Aurora-C antibody detected the Aurora-C protein (arrow).

Western blot

The anti-Aurora C antibody is used in Western blot to detect Aurora C in lysates of 293 cells expressing Flag tag (lane 1), Flag-tagged Aurora A (lane 2), Flag-tagged Aurora B (lane 3), and Flag-tagged Aurora C (lane 4). Data is kindly provided by Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).
The anti-Aurora C antibody is used in Western blot to detect Aurora C in lysates of 293 cells expressing Flag tag (lane 1), Flag-tagged Aurora A (lane 2), Flag-tagged Aurora B (lane 3), and Flag-tagged Aurora C (lane 4). Data is kindly provided by Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).

Western blot

Aurora-C Antibody (Ctr) western blot of 293 cell line lysates (35 ug/lane). The Aurora-C antibody detected the Aurora-C protein (arrow).
Aurora-C Antibody (Ctr) western blot of 293 cell line lysates (35 ug/lane). The Aurora-C antibody detected the Aurora-C protein (arrow).

Western blot

The anti-Aurora C antibody is used in Western blot to detect Aurora C in lysates of 293 cells expressing Flag tag (lane 1), Flag-tagged Aurora A (lane 2), Flag-tagged Aurora B (lane 3), and Flag-tagged Aurora C (lane 4). Data is kindly provided by Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).
The anti-Aurora C antibody is used in Western blot to detect Aurora C in lysates of 293 cells expressing Flag tag (lane 1), Flag-tagged Aurora A (lane 2), Flag-tagged Aurora B (lane 3), and Flag-tagged Aurora C (lane 4). Data is kindly provided by Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).

Western blot

Aurora-C Antibody (Ctr) western blot of 293 cell line lysates (35 ug/lane). The Aurora-C antibody detected the Aurora-C protein (arrow).
Aurora-C Antibody (Ctr) western blot of 293 cell line lysates (35 ug/lane). The Aurora-C antibody detected the Aurora-C protein (arrow).

Western blot

The anti-Aurora C antibody is used in Western blot to detect Aurora C in lysates of 293 cells expressing Flag tag (lane 1), Flag-tagged Aurora A (lane 2), Flag-tagged Aurora B (lane 3), and Flag-tagged Aurora C (lane 4). Data is kindly provided by Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).
The anti-Aurora C antibody is used in Western blot to detect Aurora C in lysates of 293 cells expressing Flag tag (lane 1), Flag-tagged Aurora A (lane 2), Flag-tagged Aurora B (lane 3), and Flag-tagged Aurora C (lane 4). Data is kindly provided by Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).


Requested From: 
Date Requested: 6/24/2018

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