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Anti-AURKB / Aurora-B Antibody (aa227-238) LS-C42572


Wt. Vol. Conc. Price
50 µg - 0.2 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular AURKB / Aurora-B Antibodies

Anti-AURKB / Aurora-B Antibody (aa227-238) IHC-plus™ LS-B1451
Rabbit Polyclonal to Human AURKB / Aurora-B
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Immunohistochemistry Image
Anti-AURKB / Aurora-B Antibody (aa1-344) IHC-plus™ LS-B2882
Sheep Polyclonal to Human AURKB / Aurora-B
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human AURKB / Aurora-B
Western blot, ELISA


Human AURKB / Aurora-B
Human (tested or 100% immunogen sequence identity)
Mouse, Rat, Bovine, Dog, Pig (at least 90% immunogen sequence identity)
IgG Polyclonal


  • Western blot (1:250 - 1:1000)
  • ELISA (1:2000 - 1:10000)

Specificity and Use

AURKB / Aurora-B antibody was raised against synthetic peptide corresponding to amino acids 227-238 of human Aurora-B kinase.
Detects Aurora-B kinase (AurB), a serine/threonine kinase which is the enzymatic core of the Chromosomal Passenger Complex (CPC). This complex functions in chromosome alignment and separation, histone modification, and cytokinesis. CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB. Two CPCs exist during mitosis- one containing all four members, and another consisting of INCENP and AurB. Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3. AurB is overexpressed in a number of tumors, including primary breast and colon tumor samples. Its expression in tumors seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.
Western Blot: LS-C42572 detects a band of approximately 39kD in HeLa cell lysates.


PBS, pH 7.2, 0.01% sodium azide.
For research use only.

About AURKB / Aurora-B

Q96GD4 NM_004217 NP_004208.2

AURKB Antibody, AIRK2 Antibody, AIK2 Antibody, Aurora kinase B Antibody, Aurora kinase B-Sv1 Antibody, Aurora-related kinase 2 Antibody, Aurora/IPL1-related kinase 2 Antibody, ARK-2 Antibody, ARK2 Antibody, Aurkb-sv1 Antibody, Aurkb-sv2 Antibody, Aurora 1 Antibody, Aurora-B Antibody, AIM-1 Antibody, IPL1 Antibody, STK-1 Antibody, STK5 Antibody, PPP1R48 Antibody, AurB Antibody, Aurora B Antibody, Aurora kinase B-Sv2 Antibody, Aurora-1 Antibody, Aurora1 Antibody, Serine/threonine kinase 12 Antibody, STK1 Antibody, STK12 Antibody

Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis.

Requested From: United States
Date Requested: 10/26/2016

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