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Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1).
Gene Name: | ataxin 1-like |
Synonyms: | ATXN1L, Ataxin-1-like, Ataxin 1-like, BOAT, BOAT1, Brother of ataxin-1, Brother of ATXN1 |
Target Sequences: | NM_001137675 NP_001131147.1 P0C7T5 |
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