Human ATXN1 / SCA1
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig
(tested or 100% immunogen sequence identity)
Chicken, Xenopus (at least 90% immunogen sequence identity)
- Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
ATXN1 / SCA1 antibody was raised against synthetic peptide C-TLKNLKNGSVKKGQ from an internal region of human ATXN1 / Ataxin-1 (NP_000323.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Bovine, Bat, Horse, Pig, Opossum (100%); Turkey, Chicken, Lizard, Xenopus (93%); Panda, Dog, Platypus, Pufferfish (86%).
- Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C139784. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human ATXN1 / Ataxin-1. Reported variants represent identical protein: NP_001121636.1, NP_000323.2
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave bands at approx 75kD and 26kD in Mouse Fetal Brain lysates after 0.5 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 84.7kD according to NP_001186234.1 and 83.8kD according to NP_033150.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.
This antibody carries the LSBio 100% Guarantee.