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Anti-ATXN1 / SCA1 Antibody (aa686-699) LS-C139784

Catalog Size Price
LS-C139784-100 100 µg Unavailable

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100% Guaranteed
Goat Polyclonal to Human ATXN1 / SCA1
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig


Human ATXN1 / SCA1
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig (tested or 100% immunogen sequence identity)
Chicken, Xenopus (at least 90% immunogen sequence identity)
Immunoaffinity purified


ELISA (1:32000)
IHC - Paraffin

Specificity and Use

ATXN1 / SCA1 antibody was raised against synthetic peptide C-TLKNLKNGSVKKGQ from an internal region of human ATXN1 / Ataxin-1 (NP_000323.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Bovine, Bat, Horse, Pig, Opossum (100%); Turkey, Chicken, Lizard, Xenopus (93%); Panda, Dog, Platypus, Pufferfish (86%).
LS-E27681 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C139784. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human ATXN1 / Ataxin-1. Reported variants represent identical protein: NP_001121636.1, NP_000323.2
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave bands at approx 75kD and 26kD in Mouse Fetal Brain lysates after 0.5 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 84.7kD according to NP_001186234.1 and 83.8kD according to NP_033150.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About ATXN1 / SCA1

P54253 NM_000332 NP_000323.2

ATXN1 Antibody, ATX1 Antibody, Ataxin 1 Antibody, D6S504E Antibody, Ataxin-1 Antibody, SCA1 Antibody

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes.

Requested From: 
Date Requested: 4/22/2018

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