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Anti-ATP2A1 / SERCA1 Antibody (aa199-505) LS-C12014

Ordering

Wt. Vol. Conc. Price
- 100 µl - $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Mouse Monoclonal (IgG1) to Rabbit ATP2A1 / SERCA1
Rabbit, Mouse, Rat, Dog, Guinea pig
Immunofluorescence, Western blot
Unconjugated

Details

Rabbit ATP2A1 / SERCA1
Mouse
Rabbit, Mouse, Rat, Dog, Guinea pig (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Ascites

Applications

Immunofluorescence (1:500), Western blot (1:2500)

Specificity and Use

ATP2A1 / SERCA1 antibody was raised against purified rabbit skeletal muscle sarcoplasmic reticulum.
aa199-505
Recognizes an epitope between amino acids 199-505 of rabbit skeletal muscle ATPase, a region that is not exposed in native sarcoplasmic reticulum. Species cross-reactivity: Rabbit, Rat, Mouse, Canine and Guinea pig.
Suitable for use in Immunofluorescence and Western Blot. Immunofluorescence: 1:500. Immunofluorescence staining of SERCA 1 ATPase in canine skeletal muscle with results in strong labeling of the entire type II (fast) myofiber. Western Blot: 1:2500. By Western Blot, this antibody detects an ~110kD protein representing SERCA 1 ATPase in canine skeletal muscle extracts.

Packaging

PBS, 0.05% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About ATP2A1 / SERCA1

O14983 NM_004320 NP_004311.1

ATP2A1 Antibody, SERCA1 Antibody, ATP2A Antibody, Calcium pump 1 Antibody, SR Ca(2+)-ATPase 1 Antibody

ATP2A1 / SERCA1 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction.

Requested From: United States
Date Requested: 10/1/2016

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