Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Mouse Monoclonal (IgG1) to Sheep ATP1A1
Sheep, Rat, Dog, Pig
IHC, Western blot
Sheep, Rat, Dog, Pig (tested or 100% immunogen sequence identity)
Specificity and Use
ATP1A1 antibody was raised against sheep kidney Na+/K+ ATPase- 1.
Recognizes the 1 subunit of rat, sheep, pig and dog Na+/K+ ATPase-. Detects a band of ~110kD by Western blot. Does not cross-react with Xenopus and chicken Na+/K+ ATPase- 1 or with rat Na+/K+ ATPase- 2. Recognizes an epitope between aa 496-506 of sheep kidney Na+/K+ ATPase-.
Immunohistochemistry (1:100). Western Blot (1:250).
ATP1A1 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle.