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ATP12A belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: | ATPase, H+/K+ transporting, nongastric, alpha polypeptide |
Family/Subfamily: | Transporter , ATPase - P type, type IIC |
Synonyms: | ATP12A, ATP1AL1, HKalpha2, Proton pump |
Target Sequences: | NM_001676 NP_001667.4 P54707 |
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