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Anti-ATM Antibody (C-Terminus) IHC-plus™ LS-B1329

Note: This antibody replaces LS-C19640

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ATM Antibodies

Anti-ATM Antibody (aa980-1512, clone 3E8) IHC-plus™ LS-B1684
Mouse Monoclonal [clone 3E8] (IgG1) to Human ATM
Human
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human ATM
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human ATM
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1 - 2 µg/ml)
  • Western blot

Specificity and Use

ATM antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human ATM.
LS-E30276 - Liquid - 50 µg - $145.00
C-Terminus
peptide corresponding to 14 amino acids near the carboxy terminus of human ATM
Immunohistochemistry: LS-B1329 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1329 was determined to be 1-2 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About ATM

Q13315 NM_000051 NP_000042.3

ATM Antibody, A-T mutated Antibody, ATA Antibody, ATC Antibody, ATD Antibody, ATE Antibody, AT mutated Antibody, Ataxia telangiectasia Antibody, ATDC Antibody, Serine-protein kinase ATM Antibody, AT1 Antibody, Ataxia telangiectasia mutated Antibody, TEL1 Antibody, TELO1 Antibody

Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism.

Immunohistochemistry

Immunohistochemistry
Anti-ATM antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1329 concentration 2 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-ATM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1329 concentration 2 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of ATM in Human Lymph Node cells with ATM antibody at 10 ug/ml.

Western blot

Western blot
Western blot of ATM in Daudi whole cell lysate with ATM antibody at (A) 1 and (B) 2 ug/ml.

Requested From: United States
Date Requested: 12/5/2016

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