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Anti-ATG4A Antibody (aa100-114) LS-C188038


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular ATG4A Antibodies

Anti-ATG4A Antibody (aa2-398) LS-C34999
Sheep Polyclonal (IgG) to Human ATG4A
Western blot, ELISA
Anti-ATG4A Antibody (C-Terminus) IHC-plus™ LS-B12105
Rabbit Polyclonal to Human ATG4A
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

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Rabbit Polyclonal (IgG) to Human ATG4A


Human ATG4A
Human (tested or 100% immunogen sequence identity)
Mouse, Rat (at least 90% immunogen sequence identity)
IgG Polyclonal
Affinity purified



Specificity and Use

ATG4A antibody was raised against kLH conjugated synthetic peptide corresponding to amino acids 100-114 of human ATG4A. The corresponding sequence differs by 2 amino acids in mouse and rat.
Recognizes human ATG4A (Autophagy-related protein 4 homolog A), otherwise known as APG4A/Cysteine protease ATG4A, a cytosolic cysteine protease and member of the peptidase C54 family, predominantly expressed in skeletal muscle and brain, which plays a central role in the cleavage of the C-Terminal region of the target proteins GABARAPL2, MAP1LC3 or GABARAP during autophagy.(AHP2220) has been shown to be suitable for use in immunoprecipitation using HEK-293T cell lysates.


PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About ATG4A

Q8WYN0 NM_052936 Q8WYN0

ATG4A Antibody, AUTL2 Antibody, Autophagin-2 Antibody, APG4A Antibody, Autophagin 2 Antibody, Cysteine protease ATG4A Antibody, HAPG4A Antibody, APG4 autophagy 4 homolog A Antibody

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Requested From: United States
Date Requested: 10/28/2016

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