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ATF7IP / MCAF1

activating transcription factor 7 interacting protein

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Facilitates telomerase TERT and TERC gene expression by SP1 in cancer cells.

Gene Name: activating transcription factor 7 interacting protein
Synonyms: ATF7IP, ATF-interacting protein, AM, ATF7-interacting protein, ATF-IP, MCAF1, p621, ATFa-associated modulator, HAM, MCAF
Target Sequences: NM_018179 NP_060649.3 Q6VMQ6

☰ Filters
Antibodies (10)
Primary (10)
ATF7IP / MCAF1 (10)
Human (9)
Mouse (5)
IHC (3)
IHC-P (1)
WB (8)
ICC (1)
IF (1)
IP (1)
rabbit (9)
mouse (1)
IgG (3)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (9)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (7)
aa553-602 (4)
aa25-100 (3)
No (10)
Select
ATF7IP / MCAF1 Rabbit anti-Human Polyclonal (aa25-100) Antibody
Human
IHC, IP, WB
Unconjugated
100 µl/$867
ATF7IP / MCAF1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ATF7IP / MCAF1 Rabbit anti-Mouse Polyclonal (aa553-602) Antibody
Mouse
WB
Unconjugated
100 µl/$424
ATF7IP / MCAF1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ATF7IP / MCAF1 Rabbit anti-Mouse Polyclonal (aa553-602) (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$469
ATF7IP / MCAF1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ATF7IP / MCAF1 Rabbit anti-Mouse Polyclonal (aa553-602) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$469
ATF7IP / MCAF1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ATF7IP / MCAF1 Rabbit anti-Mouse Polyclonal (aa553-602) (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$469
ATF7IP / MCAF1 Antibody - Detection of Human MCAF by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-MCAF used at a dilution of 1:1000 (1 Detection: DAB.
Select
ATF7IP / MCAF1 Rabbit anti-Human Polyclonal (aa25-100) Antibody
Human
IHC, WB
Unconjugated
10 µl/$295; 100 µl/$514
ATF7IP / MCAF1 Antibody - Immunofluorescence staining of ATF7IP in U251MG cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human ATF7IP polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
Select
ATF7IP / MCAF1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
ATF7IP / MCAF1 Antibody - Detection of Human MCAF by Immunohistochemistry. Sample: FFPE section of human small cell lung cancer. Antibody: Affinity purified rabbit anti-MCAF used at a dilution of 1:250.
Select
ATF7IP / MCAF1 Rabbit anti-Human Polyclonal (aa25-100) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
2.5 µg/$295; 100 µl/$532
Select
ATF7IP / MCAF1 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
50 µg/$558
Select
ATF7IP / MCAF1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-10 of 10 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).