ASPN / Asporin

asporin

Negatively regulates periodontal ligament (PDL) differentiation and mineralization to ensure that the PDL is not ossified and to maintain homeostasis of the tooth-supporting system. Inhibits BMP2-induced cytodifferentiation of PDL cells by preventing its binding to BMPR1B/BMP type-1B receptor, resulting in inhibition of BMP-dependent activation of SMAD proteins (By similarity). Critical regulator of TGF-beta in articular cartilage and plays an essential role in cartilage homeostasis and osteoarthritis (OA) pathogenesis. Negatively regulates chondrogenesis in the articular cartilage by blocking the TGF-beta/receptor interaction on the cell surface and inhibiting the canonical TGF-beta/Smad signal. Binds calcium and plays a role in osteoblast-driven collagen biomineralization activity.

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Products

Antibodies (31)

ELISA Kits (17)

Proteins (3)

Type

Competitive EIA (1)

Custom (3)

Primary (31)

Recombinant (3)

Sandwich (12)

Sandwich CLIA (1)

Target

ASPN / Asporin (51)

Reactivity

Human (30)

Mouse (17)

Rat (6)

Chicken (1)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (1)

Monkey (5)

Porcine (1)

Rabbit (4)

Sheep (1)

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Application

IHC (7)

IHC-P (7)

WB (27)

ELISA (6)

ICC (1)

IF (3)

Peptide-ELISA (2)

Host

rabbit (29)

mouse (1)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (19)

Clonality

polyclonal pc (31)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (15)

APC (1)

APC Conjugated (2)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (13)

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Epitope

aa16-373 (8)

aa250-299 (4)

C-Terminus (2)

aa182-194 (1)

aa242-269 (1)

Publications

No (51)

Sample Type

Plasma (8)

Serum (8)

Tissue Homogenates (2)

Tag

6His-SUMO, N-terminus (1)

GST (1)

His-GST, N-terminus (1)

Species

Human (2)

Mouse (1)

Source

E. coli (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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ASPN / Asporin Antibody (aa242-269) LS-C99335

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal (aa242-269) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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ASPN / Asporin Antibody (aa182-194) LS-C54549

Antibody:

ASPN / Asporin Goat anti-Human Polyclonal (aa182-194) Antibody

Reactivity:

Human, Monkey

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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ASPN / Asporin Antibody (aa250-299) LS-C31930

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal (aa250-299) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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ASPN / Asporin Antibody (aa250-299, HRP) LS-C443825

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal (aa250-299) (HRP) Antibody

Reactivity:

Rabbit, Dog, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

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ASPN / Asporin Antibody (aa250-299, Biotin) LS-C443823

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal (aa250-299) (Biotin) Antibody

Reactivity:

Rabbit, Dog, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

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ASPN / Asporin Antibody (aa250-299, FITC) LS-C443824

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal (aa250-299) (FITC) Antibody

Reactivity:

Rabbit, Dog, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Mouse ASPN / Asporin Protein (Recombinant His-GST, N-terminus) (aa16-373) - LS-G24781

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

70.9 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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ASPN / Asporin Antibody (C-Terminus) LS-C153382

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

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IHC-plus™ ASPN / Asporin Antibody LS-B15918

(4.0) Rating

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

Human ASPN / Asporin (Sandwich ELISA) ELISA Kit - LS-F6536

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$834

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ASPN / Asporin Antibody LS-C497019

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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Human ASPN / Asporin Protein (Recombinant 6His-SUMO, N-terminus) (aa33-380) - LS-G56102

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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IHC-plus™ ASPN / Asporin Antibody LS-B15799

(4.0) Rating

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

60 µl/$460

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ASPN / Asporin Antibody (C-Terminus) LS-C144892

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

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ASPN / Asporin Antibody LS-C803846

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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ASPN / Asporin Antibody LS-C832828

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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ASPN / Asporin Antibody (aa16-373) LS-C372939

Antibody:

ASPN / Asporin Rabbit anti-Mouse Polyclonal (aa16-373) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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ASPN / Asporin Antibody (aa16-373, HRP) LS-C711355

Antibody:

ASPN / Asporin Rabbit anti-Mouse Polyclonal (aa16-373) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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ASPN / Asporin Antibody (aa16-373, Biotin) LS-C686986

Antibody:

ASPN / Asporin Rabbit anti-Mouse Polyclonal (aa16-373) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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ASPN / Asporin Antibody (aa16-373, FITC) LS-C693771

Antibody:

ASPN / Asporin Rabbit anti-Mouse Polyclonal (aa16-373) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

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ASPN / Asporin Antibody (aa16-373, APC) LS-C717729

Antibody:

ASPN / Asporin Rabbit anti-Mouse Polyclonal (aa16-373) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

ASPN / Asporin Antibody (aa16-373, APC, Cy7) LS-C734373

Antibody:

ASPN / Asporin Rabbit anti-Mouse Polyclonal (aa16-373) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781

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ASPN / Asporin Antibody (aa16-373, PE) LS-C725417

Antibody:

ASPN / Asporin Rabbit anti-Mouse Polyclonal (aa16-373) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

ASPN / Asporin Antibody (aa16-373, Cy3) LS-C702328

Antibody:

ASPN / Asporin Rabbit anti-Mouse Polyclonal (aa16-373) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• APC, Cy7
• PE
• More...
  • Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • APC, Cy7
  • PE
  • Cy3

Select

ASPN / Asporin Antibody LS-C309538

Antibody:

ASPN / Asporin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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