Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ASL Antibody, ASAL Antibody, Argininosuccinate lyase Antibody, Argininosuccinase Antibody, Arginosuccinase Antibody
ASL / Argininosuccinate Lyase encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.
IHC of paraffin-embedded C2C12 xenograft using ASL antibody at 1:500 dilution.
IHC of paraffin-embedded U87 xenograft using ASL antibody at 1:500 dilution.
Immunofluorescence of paraformaldehyde-fixed HeLa using Arginosuccinate Lyase antibody at 1:200 dilution.
ASL antibody detects ASL protein by Western blot analysis. A. 30 ug Neuro2A whole lysate/extract. B. 30 ug GL261 whole cell lysate/extract. C. 30 ug C8D30 whole cell lysate/extract. D. 30 ug NIH-3T3 whole cell lysate/extract. E. 30 ug BCL-1 whole cell lysate/extract. F. 30 ug Raw264.7 whole cell lysate/extract. G. 30 ug C2C12 whole cell lysate/extract. 10 % SDS-PAGE. ASL antibody dilution:1:1000
Sample (30 ug of whole cell lysate). A: HeLa, B: Hep G2 . 10% SDS PAGE. Arginosuccinate Lyase / ASL antibody diluted at 1:1000.
Requested From: United States
Date Requested: 2/22/2017