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ASIP

agouti signaling protein

Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.

Gene Name: agouti signaling protein
Synonyms: ASIP, Agouti-signaling protein, AGTIL, Agouti signaling protein, AGTI, Agouti switch protein, AGSW, SHEP9, ASP, Nonagouti homolog
Target Sequences: NM_001672 NP_001663.2 P42127

☰ Filters
Antibodies (13)
Proteins (5)
Over-Expression Lysate (2)
Primary (13)
Recombinant (3)
ASIP (18)
Human (11)
Mouse (4)
IHC (4)
IHC-P (1)
WB (1)
ELISA (7)
ICC (1)
IF (4)
Peptide-ELISA (1)
rabbit (13)
IgG (13)
polyclonal pc (13)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (10)
N-Terminus (2)
aa1-40 (2)
No (18)
6His-SUMO, N-terminus (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Cow (1)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Select
ASIP Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA
Unconjugated
100 µl/$801
Select
ASIP Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA
Unconjugated
100 µg/$832
ASIP Antibody - Paraffin-embedding Immunohistochemistry using human endometrial cancer at dilution 1:100
Select
ASIP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
ASIP Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ASIP Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
ASIP Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ASIP Antibody - Immunohistochemistry of paraffin-embedded human prostate cancer tissue.
Select
ASIP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
ASIP Rabbit anti-Human Polyclonal (aa1-40) Antibody
Human
ICC, IHC
Unconjugated
50 µl/$860
Select
ASIP Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
ASIP Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ASIP Antibody - Western blot analysis of ASIP using 293 whole lysates.
Select
ASIP Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
ASIP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
ASIP Rabbit anti-Human Polyclonal (aa1-40) Antibody
Human
ELISA
Unconjugated
400 µg/$860
ASIP Protein - Purified recombinant protein ASIP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
12 kDa
20 µg/$1,107
ASIP Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
ASIP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
2 µg/$439
ASIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
14.52 kDa
100 µg/$494
ASIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
14.52 kDa
20 µg/$150
Viewing 1-18 of 18 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).