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Anti-ARRB2 / Beta Arrestin 2 Antibody (aa351-361) LS-C54486

Note: This antibody replaces LS-C69278

Ordering

Wt. Vol. Conc. Price
100 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ARRB2 / Beta Arrestin 2 Antibodies

Anti-ARRB2 / Beta Arrestin 2 Antibody (clone 3G1) IHC-plus™ LS-B6008
Mouse Monoclonal [clone 3G1] (IgG2a,k) to Human ARRB2 / Beta Arrestin 2
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-ARRB2 / Beta Arrestin 2 Antibody (aa23-40) IHC-plus™ LS-B7973
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-ARRB2 / Beta Arrestin 2 Antibody (aa262-430, FITC) LS-C303425
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Human
Western blot, ELISA
FITC Conjugated
Western blot Image

100% Guaranteed 100% Guaranteed Publications Publications (2)
Goat Polyclonal to Human ARRB2 / Beta Arrestin 2
Human
Western blot, ELISA
Unconjugated

Details

Human ARRB2 / Beta Arrestin 2
Goat
Human (tested or 100% immunogen sequence identity)
Monkey, Mouse, Rat, Bovine, Hamster, Horse (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.03 - 0.1 µg/ml)
  • ELISA (1:32000)

  • IHC - Paraffin

Specificity and Use

ARRB2 / Beta Arrestin 2 antibody was raised against synthetic peptide C-HDHIPLPRPQS from an internal region of human ARRB2 / Beta-Arrestin 2 (NP_004304.1; NP_945355.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Marmoset, Mouse, Rat, Hamster, Bovine, Horse (91%); Monkey, Rabbit (82%).
LS-E25872 - Lyophilized - 100 µg - $145.00
aa351-361
Human ARRB2 / Beta-Arrestin 2. This antibody is expected to recognise both reported isoforms NP_004304.1 and NP_945355.1. No crossreactivity is expected with Arrestin beta 1.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

Publications (2)

1
Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia. Napolitano F, Pasqualetti M, Usiello A, Santini E, Pacini G, Sciamanna G, Errico F, Tassone A, Di Dato V, Martella G, Cuomo D, Fisone G, Bernardi G, Mandolesi G, Mercuri NB, Standaert DG, Pisani A. Neurobiology of disease. 2010 38:434-45. [PubMed:20227500]
2
Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys. Zakrzewicz A, Krasteva G, Wilhelm J, Dietrich H, Wilker S, Padberg W, Wygrecka M, Grau V. Immunobiology. 2011 216:854-61. [PubMed:21193245]

About ARRB2 / Beta Arrestin 2

P32121 NM_004313 NP_004304.1

ARRB2 Antibody, Arrestin 3 Antibody, Arrestin beta-2 Antibody, ARB2 Antibody, ARR2 Antibody, BARR2 Antibody, Arrestin, beta 2 Antibody, Beta-arrestin-2 Antibody

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors.

Western blot

Western blot
Antibody (0.03 ug/ml) staining of Human Spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
 

Requested From: United States
Date Requested: 12/10/2016

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