Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Specificity and Use
ARID1A / BAF250 antibody was raised against the epitope recognized by this antibody maps to a region between residue 750 and 800 of human AT rich interactive domain 1A (BRG1-associated factor 250kD) using the numbering given in entry NP_006006.3 (GeneID 8289).
Species cross-reactivity: Human. Other species have not been tested.
ARID1A Antibody, BAF250 Antibody, BAF250a Antibody, BRG1-associated factor 250a Antibody, C1orf4 Antibody, BRG1-associated factor 250 Antibody, ELD Antibody, HOSA1 Antibody, Osa homolog 1 Antibody, OSA1 Antibody, OSA1 nuclear protein Antibody, SMARCF1 Antibody, MRD14 Antibody, p270 Antibody, B120 Antibody, BM029 Antibody, Brain protein 120 Antibody, C10rf4 Antibody, HELD Antibody, SWI-like protein Antibody, SWI/SNF complex protein p270 Antibody
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Binds DNA non-specifically. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.