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ARHGEF3 / XPLN

Rho guanine nucleotide exchange factor (GEF) 3

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Rho guanine nucleotide exchange factor (GEF) 3
Synonyms: ARHGEF3, 59.8 kDA protein, DKFZP434F2429, GEF3, STA3, RhoGEF protein, XPLN
Target Sequences: NM_019555 NP_062455.1 Q9NR81

☰ Filters
Antibodies (20)
Proteins (8)
Over-Expression Lysate (6)
Primary (20)
Recombinant (2)
ARHGEF3 / XPLN (28)
Human (20)
Mouse (7)
Rat (4)
Monkey (1)
IHC (14)
IHC-P (4)
WB (19)
ELISA (11)
ICC (2)
IF (2)
Peptide-ELISA (3)
rabbit (19)
mouse (1)
IgG (16)
polyclonal pc (20)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (15)
aa211-240 (7)
430-510 aa, C-terminal (1)
C-Terminus (1)
aa3-194 (1)
aa439-488 (1)
aa456-505 (1)
No (28)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (5)
293T Cells (3)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
ARHGEF3 / XPLN Antibody - Western blot of XPLN antibody
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (430-510 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ARHGEF3 / XPLN Antibody - Western blot analysis of lysates from COLO cells, using ARHGEF3 Antibody. The lane on the right is blocked with the synthesized peptide.
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa456-505) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ARHGEF3 / XPLN Antibody - Immunohistochemical analysis of XPLN staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
ARHGEF3 / XPLN Antibody - Immunohistochemistry of paraffin-embedded human ovarian cancer at dilution 1:100
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa211-240) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa211-240) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa211-240) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa211-240) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa211-240) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa211-240) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ARHGEF3 / XPLN Antibody
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa3-194) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
ARHGEF3 / XPLN Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
ARHGEF3 / XPLN Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ARHGEF3 / XPLN Antibody - ARHGEF3 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa211-240) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ARHGEF3 / XPLN Antibody - Immunohistochemistry of paraffin-embedded mouse brain tissue.
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ARHGEF3 / XPLN Antibody - Western blot analysis of extracts from COLO cells, using ARHGEF3 antibody.
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
ARHGEF3 / XPLN Antibody - Western blot analysis of the lysates from HeLa cells using ARHGEF3 antibody.
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal (aa439-488) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ARHGEF3 / XPLN Antibody - Anti-XPLN Antibody at 1:1000 dilution + human brain lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 60 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Select
ARHGEF3 / XPLN Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$386
Select
ARHGEF3 / XPLN Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
ARHGEF3 / XPLN Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ARHGEF3 / XPLN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
63.6 kDa
20 µg/$150
ARHGEF3 / XPLN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
60.6 kDa
20 µg/$150
ARHGEF3 / XPLN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
59.6 kDa
20 µg/$150
ARHGEF3 / XPLN Protein - 12.5% SDS-PAGE of human ARHGEF3 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
63.4 kDa
10 µg/$479; 25 µg/$670
Viewing 1-25 of 28 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).