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ARHGAP35 / GRLF1
Rho GTPase activating protein 35
The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids.
| Gene Name: | Rho GTPase activating protein 35 |
| Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
| Synonyms: | ARHGAP35, GRF-1, p190-A, p190A, p190ARhoGAP, Rho GAP p190A, p190RhoGAP, GRF1, GRLF1, KIAA1722 |
| Target Sequences: | NM_004491 NP_004482.4 Q9NRY4 |
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(23)
Proteins
(3)
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Over-Expression Lysate
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Primary
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ARHGAP35 / GRLF1
(26)
Reactivity
Human
(23)
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(20)
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(19)
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(3)
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(3)
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(3)
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(4)
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(3)
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(3)
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(8)
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(2)
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(19)
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rabbit
(22)
mouse
(1)
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(13)
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(1)
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monoclonal mc
(1)
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(22)
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(1)
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(1)
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(1)
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(20)
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(4)
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(4)
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(3)
1040-1120 aa
(2)
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(1)
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(1)
Tyr1105
(1)
aa1032-1081
(1)
aa1071-1120
(1)
aa1200-1250
(1)
Publications
No
(26)
Tag
GST
(1)
Myc-DDK (Flag)
(2)
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Human
(2)
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293T Cells
(1)
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(1)
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(1)
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Purified
(1)
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (1040-1120 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (pTyr1105) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (pTyr1105) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (pTyr1105) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$688
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (pTyr1105) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (1040-1120 aa) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (aa1071-1120) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (Ab-1105) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
100 µg/$357
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (pTyr1087) Antibody
Mouse, Rat, Human
ELISA, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (pTyr1087) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (aa1032-1081) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (aa1200-1250) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ARHGAP35 / GRLF1 Mouse anti-Human Monoclonal (4D4-F8) Antibody
Human
ELISA
Unconjugated
100 µg/$423
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µg/$305; 100 µg/$357
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (aa44-93) Antibody
Human
WB
Unconjugated
100 µl/$424
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (aa44-93) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (aa44-93) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (aa44-93) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (pTyr1087) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$328; 100 µl/$419
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (Tyr1105) Antibody
Human
WB
Unconjugated
400 µl/$393
ARHGAP35 / GRLF1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Rat, Pig, Human
WB
Unconjugated
100 µl/$315
293T Cells
Myc-DDK (Flag)
172.18 kDa
20 µg/$215
Wheat Germ Extract
GST
29.7 kDa
10 µg/$479; 25 µg/$670
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product results
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