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Anti-ARH / LDLRAP1 Antibody (clone 4G4-D5) IHC-plus™ LS-B4523
Note: This antibody replaces LS-C105129Most Popular ARH / LDLRAP1 Antibodies
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Details
| Human ARH / LDLRAP1 | |
| Mouse | |
| Human (tested or 100% immunogen sequence identity) | |
| IgG1,k Monoclonal [4G4-D5] | |
| Unconjugated | |
| Purified from ascites by Protein A | |
| Unmodified |
Applications
- IHC - Paraffin (5 µg/ml)
- Immunofluorescence (10 µg/ml)
- Western blot
- ELISA
Specificity and Use
| ARH / LDLRAP1 antibody was raised against lDLRAP1 (AAH29770, 1 a.a. ~ 264 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Western Blot (Cell lysate) - positive control Hela NE. Western Blot (Transfected lysate) - positive control transfected 293T cell line. Immunofluorescence (10 ug/ml) - positive control HeLa cells. |
Packaging
| PBS, pH 7.2 | |
| Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. | |
| For research use only. |
About ARH / LDLRAP1
Q5SW96
NP_056442.2
LDLRAP1 Antibody, ARH Antibody, ARH1 Antibody, FHCB1 Antibody, FHCB2 Antibody, LDL receptor adaptor protein Antibody, ARH2 Antibody
Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits.
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Requested From:
Date Requested: 6/27/2017
Date Requested: 6/27/2017
