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ARFGEF1

ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)

Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure; the function may be independent of its GEF activity. Required for the maturaion of integrin beta-1 in the Golgi. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and PKA pathways. Inhibits GAP activity of MYO9B probably through competetive RhoA binding. The function in the nucleus remains to be determined.

Gene Name: ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
Synonyms: ARFGEF1, ARFGEP1, BIG1, Brefeldin A-inhibited GEP 1, p200, p200 ARF-GEP1, DKFZP434L057
Target Sequences: NM_006421 NP_006412.2 Q9Y6D6

☰ Filters
Antibodies (7)
Proteins (1)
Primary (7)
Recombinant (1)
ARFGEF1 (8)
Human (7)
Mouse (5)
Rat (4)
Bat (3)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Orangutan (3)
Pig (3)
Rabbit (3)
Zebrafish (3)
IHC (3)
WB (6)
ELISA (1)
IP (1)
rabbit (7)
IgG (3)
polyclonal pc (7)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (4)
aa312-361 (4)
aa1800-C-term (2)
No (8)
GST, N-terminus (1)
Human (1)
Wheat Germ Extract (1)
ARFGEF1 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using ARFGEF1 Polyclonal Antibody at dilution of 1:40(×200)
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ARFGEF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ARFGEF1 Antibody - Detection of Human BIG1/ARFGEF1 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BIG1/ARFGEF1 used at a dilution of 1:1000 (1 ug/ml).
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ARFGEF1 Rabbit anti-Human Polyclonal (aa1800-C-term) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ARFGEF1 Antibody - Detection of Human BIG1/ARFGEF1 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BIG1/ARFGEF1 used at a dilution of 1:250. Epitope Retrieval Buffer-High pH (IHC-101J) was substituted for Epitope Retrieval Buffer-Reduced pH.
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ARFGEF1 Rabbit anti-Human Polyclonal (aa1800-C-term) Antibody
Human
IHC
Unconjugated
2.5 µg/$295; 100 µl/$532
ARFGEF1 Antibody - Western blot of Human Fetal Liver. ARFGEF1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ARFGEF1 Rabbit anti-Human Polyclonal (aa312-361) Antibody
Human
WB
Unconjugated
100 µl/$424
ARFGEF1 Antibody - Western blot of Human Fetal Liver. ARFGEF1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ARFGEF1 Rabbit anti-Human Polyclonal (aa312-361) (HRP) Antibody
Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
HRP Conjugated
100 µl/$469
ARFGEF1 Antibody - Western blot of Human Fetal Liver. ARFGEF1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ARFGEF1 Rabbit anti-Human Polyclonal (aa312-361) (Biotin) Antibody
Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
ARFGEF1 Antibody - Western blot of Human Fetal Liver. ARFGEF1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ARFGEF1 Rabbit anti-Human Polyclonal (aa312-361) (FITC) Antibody
Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
FITC Conjugated
100 µl/$469
ARFGEF1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-8 of 8 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).