AR / Androgen Receptor

androgen receptor

The androgen receptor (AR) is a NR3 Steroid Receptor located on the X chromosome. AR is a phosphoprotein and acts as a steroid hormone-activated transcription factor for androgen-responsive genes. Mutations in the AR gene are associated with androgen insensitivity syndrome (CAIS) or testicular feminization syndrome, Reifenstein syndrome, and Kennedy spinal and bulbar muscular atrophy. They lead to symptoms such as low virilization, reduced sperm production, testicular atrophy, and infertility. Androgen signaling through the androgen receptor (AR) appears to be involved in all aspects of prostate cancer, from initiation to development of treatment resistance. Gain-of-function AR gene mutations and/or altered signaling through AR have been suggested to contribute to disease progression. A recent study showed decreased expression of AR in response to incubation of LNCaP prostate carcinoma cells with PC-SPES, a mixture of eight herbs (Bonham et al. 2002). Two forms of AR that differ in their N termini have been isolated: AR A (87 kD), which is derived from translation of an internal methionine codon (met188), and AR B (110 kD). The two isoforms are expressed in similar tissues; however, AR B generally is the more abundant form.

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Antibodies (169)

ELISA Kits (25)

Proteins (12)

Type

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Development Kit (1)

DNA Binding Phosphorylation (2)

Over-Expression Lysate (4)

Primary (169)

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Sandwich (14)

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AR / Androgen Receptor (206)

Reactivity

Human (171)

Mouse (49)

Rat (37)

Bovine (4)

Chicken (1)

Chimpanzee (3)

Dog (5)

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aa420-659 (12)

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160-240 aa (1)

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Ab-94 (1)

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Plasma (11)

Serum (11)

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Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

6His, N-terminus (1)

GST, N-terminus (1)

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His (2)

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Species

Human (8)

Mouse (1)

Rat (2)

Source

293T Cells (2)

E. coli (7)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

IHC-plus™ AR / Androgen Receptor Antibody (aa611-660) LS-B13271

(4.0) Rating

Antibody:

AR / Androgen Receptor Rabbit anti-Human Polyclonal (aa611-660) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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AR / Androgen Receptor Antibody (N-Terminus, clone SP107) LS-C210358

Antibody:

AR / Androgen Receptor Rabbit anti-Human Monoclonal (N-Terminus) (SP107) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

500 µl/$548

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AR / Androgen Receptor Antibody (C-Terminus, clone SP242) LS-C210456

Antibody:

AR / Androgen Receptor Rabbit anti-Human Monoclonal (C-Terminus) (SP242) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

500 µl/$562

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AR / Androgen Receptor Antibody (aa2-16) LS-C20122

Antibody:

AR / Androgen Receptor Goat anti-Human Polyclonal (aa2-16) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Pig, Human

Applications:

IF, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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AR / Androgen Receptor Antibody (phospho-Tyr267) LS-C209425

Antibody:

AR / Androgen Receptor Rabbit anti-Human Polyclonal (pTyr267) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$567

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IHC-plus™ AR / Androgen Receptor Antibody (clone 2H8) LS-B4133

(4.0) Rating

Antibody:

AR / Androgen Receptor Mouse anti-Human Monoclonal (2H8) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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AR / Androgen Receptor Antibody (aa1-50) LS-C290616

Antibody:

AR / Androgen Receptor Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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Human AR / Androgen Receptor Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (aa551-919) - LS-G56096

Source:

E. coli

Tag:

10His-SUMO, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F16608

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human AR / Androgen Receptor (CLIA) ELISA Kit - LS-F29439

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

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Human AR / Androgen Receptor Protein (Recombinant 6His, N-terminus) (Met1-Gln556) - LS-G26987

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

62 kDa

Price:

10 µg/$283; 50 µg/$355; 100 µg/$428

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Human AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F4505

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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Rat AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F6438

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$856

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Mouse/Human/Rat Phospho-AR / Androgen Receptor (Ser650) (DNA-Binding Phosphorylation ELISA) ELISA Kit - LS-F855

Type:

DNA Binding Phosphorylation

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$735

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AR / Androgen Receptor Antibody (clone 1G3) LS-C133049

Antibody:

AR / Androgen Receptor Mouse anti-Human Monoclonal (1G3) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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AR / Androgen Receptor Antibody LS-C331862

Antibody:

AR / Androgen Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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AR / Androgen Receptor Antibody (aa300-316, clone AR441, Azide-free, BSA-free) LS-C390448

Antibody:

AR / Androgen Receptor Mouse anti-Human Monoclonal (aa300-316) (Azide-free, BSA-free) (AR441) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

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Human AR / Androgen Receptor Protein (Recombinant GST, N-terminus) (aa221-320) - LS-G57794

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F21949

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human AR / Androgen Receptor (Cell-Based ELISA) ELISA Kit - LS-F1796

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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AR / Androgen Receptor Antibody (aa300-316, clone AR441 + DHTR/882) LS-C390460

Antibody:

AR / Androgen Receptor Mouse anti-Human Monoclonal (aa300-316) (AR441 + DHTR/882) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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AR / Androgen Receptor Antibody (phospho-Ser515) LS-C153375

Antibody:

AR / Androgen Receptor Rabbit anti-Human Polyclonal (pSer515) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

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AR / Androgen Receptor Antibody (phospho-Ser650) LS-C353892

Antibody:

AR / Androgen Receptor Rabbit anti-Human Polyclonal (pSer650) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$315

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AR / Androgen Receptor Antibody (aa660-919, clone TS106) LS-C191421

Antibody:

AR / Androgen Receptor Mouse anti-Human Monoclonal (aa660-919) (TS106) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µg/$884

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AR / Androgen Receptor Antibody (aa661-920, clone 11n6, PE) LS-C184175

Antibody:

AR / Androgen Receptor Mouse anti-Human Monoclonal (aa661-920) (PE) (11n6) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo

Format:

PE Conjugated

Price:

100 Tests/$832

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