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Anti-AQP4 / Aquaporin 4 Antibody (aa280-296) LS-C3808

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Wt. Vol. Conc. Price
- 50 µl - $375
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Rabbit Polyclonal (IgG) to Rat AQP4 / Aquaporin 4
Rat
IHC, Western blot, ELISA
Unconjugated

Details

Rat AQP4 / Aquaporin 4
Rabbit
Rat (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
IgG Polyclonal
Antiserum

Applications

IHC, Western blot (1:1000 - 1:5000), ELISA (1:10000 - 1:50000)

Specificity and Use

AQP4 / Aquaporin 4 antibody was raised against synthetic peptide 17aa sequence corresponding to aa280-296 in the region near the carboxy terminus of the rat AQP4 (1,2) (KLH coupled via cysteine amino terminal). This peptide is predicted to be cytoplasmic (2).
aa280-296
Recognizes rat Aquaporin 4 (AQ, WCH4; MIWC). Immunizing sequence is unique to AQP4. Species sequence Homology: mouse: 94%; bovine 88%: rabbit: 86%: human: 82%.
Suitable for use in ELISA, Immunohistochemistry and Western Blot.

Packaging

PBS, 0.05% sodium azide, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About AQP4 / Aquaporin 4

P55087 NM_001650 NP_001641.1

AQP4 Antibody, Aquaporin type4 Antibody, Aquaporin 4 Antibody, Aquaporin-4 Antibody, HMIWC2 Antibody, MIWC Antibody, WCH4 Antibody, AQP-4 Antibody

AQP4, also known as Mercurial-insensitive water channel (MIWC), is the fourth member of the aquaporin water channel family. This osmoreceptor regulates body water balance and mediates water flow within the central nervous system. It appears to play some specific role in the functioning of skeletal muscles, retina, and auditory system. Contrary to other aquaporin family members, AQP4 is not inhibited by mercurial compounds.

Requested From: United States
Date Requested: 9/29/2016

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