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Anti-APP / Beta Amyloid Precursor Antibody (clone MOAB-2, DY550) LS-C181970

Ordering

Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular APP / Beta Amyloid Precursor Antibodies

Anti-APP / Beta Amyloid Precursor Antibody (Thr668) IHC-plus™ LS-B1462
Rabbit Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-APP / Beta Amyloid Precursor Antibody (aa18-289, clone J4H9) IHC-plus™ LS-B2970
Mouse Monoclonal [clone J4H9] (IgG2b,k) to Human APP / Beta Amyloid Precursor
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-APP / Beta Amyloid Precursor Antibody (C-Terminus) LS-C193927
Rabbit Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human, Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone MOAB-2] (IgG2b) to Human APP / Beta Amyloid Precursor
Human, Mouse
IHC - Paraffin, ICC, Western blot, Immunoprecipitation, ELISA (applications tested for the base form of this product only)
DY550 Conjugated

Details

Human APP / Beta Amyloid Precursor
Mouse
Human, Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [MOAB-2]
DyLight 550. Also available Unconjugated or conjugated with Biotin, DY650, DY488.
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (1:500)
  • ICC (1:500)
  • Western blot (1:1000)
  • Immunoprecipitation (1:200)
  • ELISA (1:100 - 1:1000)
  • (applications tested for the base form of this product only)

Specificity and Use

APP / Beta Amyloid Precursor antibody was raised against recombinant human beta Amyloid 42.
Unaggregated, oligomeric and fibrillar forms of beta Amyloid 42 and unaggregated beta Amyloid 40. Does not detect APP.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

50 mM sodium borate
Store at 4°C in the dark.
For research use only.

About APP / Beta Amyloid Precursor

P05067 NM_000484 NP_000475.1

APP Antibody, ABPP Antibody, A4 Antibody, ABETA Antibody, AD1 Antibody, Alzheimer disease Antibody, Amyloid beta Antibody, Beta-amyloid peptide Antibody, APPI Antibody, Beta amyloid Antibody, CVAP Antibody, AAA Antibody, PN2 Antibody, PreA4 Antibody, Amyloid beta A4 protein Antibody, Peptidase nexin-II Antibody, CTFgamma Antibody, PN-II Antibody, Protease nexin-II Antibody

Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP.

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry: beta Amyloid Antibody (MOAB-2) - IHC of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunocytochemistry

Immunocytochemistry
Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice. Scale bar 20 um (from PMID: 22423893). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Western Blot: beta Amyloid Antibody (MOAB-2) - Western blot of cell lysates from HEK-APP SWE/BACE1 cells probed with an antibody against the C-terminus of APP (Lanes 1 and 2) and beta Amyloid (MOAB-2, Lanes 3 and 4). Beta Amyloid (MOAB-2) does not detect APP (from PMID: 22423893). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Western Blot: beta Amyloid Antibody (MOAB-2) - Western blot of beta Amyloid (MOAB-2) antibody in 1) 100 pmole beta Amyloid 42, 2) 5xFAD mouse brain homogenate Repetition 1 and 3) 5xFAD mouse brain homogenate Repetition 2. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/4/2016

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