Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 6F/3D] (IgM) to Human APP / Beta Amyloid Precursor
IHC - Paraffin
Human APP / Beta Amyloid Precursor
Human (tested or 100% immunogen sequence identity)
IgM Monoclonal [6F/3D]
Tissue culture supernatant
IHC - Paraffin (1:25 - 1:50)
Specificity and Use
APP / Beta Amyloid Precursor antibody was raised against recombinant fusion protein representing the extracellular region of APP between the Kunitz protease inhibitor domain and the beta-amyloid region.
Amyloid precursor protein. Species Crossreactivity: Human.
Immunohistochemistry (Paraffin): 1:25-1:50 for 1 hr at RT.
Lyophilized from 15 mM sodium azide
1,000 µl Distilled water
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP.