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Anti-APP / Beta Amyloid Precursor Antibody (C-Terminus) LS-C42809

Ordering

Wt. Vol. Conc. Price
- 100 µl - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular APP / Beta Amyloid Precursor Antibodies

Anti-APP / Beta Amyloid Precursor Antibody (Thr668) IHC-plus™ LS-B1462
Rabbit Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-APP / Beta Amyloid Precursor Antibody (aa18-289, clone J4H9) IHC-plus™ LS-B2970
Mouse Monoclonal [clone J4H9] (IgG2b,k) to Human APP / Beta Amyloid Precursor
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-APP / Beta Amyloid Precursor Antibody (C-Terminus) LS-C193927
Rabbit Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human, Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human
Western blot, ELISA
Unconjugated

Details

Human APP / Beta Amyloid Precursor
Goat
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Unmodified

Applications

  • Western blot (1:5000)
  • ELISA (1:25000)

Specificity and Use

APP / Beta Amyloid Precursor antibody was raised against synthetic peptide corresponding to amino acids 681-695 at the C-terminus of APP.
C-Terminus
Recognizes amyloid precursor protein, a large membrane protein whose C-terminus is broken down to form b amyloid in Alzheimer's disease. APP also inhibits Notch signaling through it's interaction with NUMB.

Packaging

Serum, 0.09% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About APP / Beta Amyloid Precursor

P05067 NM_000484 NP_000475.1

APP Antibody, ABPP Antibody, A4 Antibody, ABETA Antibody, AD1 Antibody, Alzheimer disease Antibody, Amyloid beta Antibody, Beta-amyloid peptide Antibody, APPI Antibody, Beta amyloid Antibody, CVAP Antibody, AAA Antibody, PN2 Antibody, PreA4 Antibody, Amyloid beta A4 protein Antibody, Peptidase nexin-II Antibody, CTFgamma Antibody, PN-II Antibody, Protease nexin-II Antibody

Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP.

Requested From: United States
Date Requested: 12/8/2016

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