Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Goat Polyclonal to Human APP / Beta Amyloid Precursor
Western blot, ELISA
Human APP / Beta Amyloid Precursor
Human (tested or 100% immunogen sequence identity)
Specificity and Use
APP / Beta Amyloid Precursor antibody was raised against synthetic peptide equivalent to aa339-348 of the C-terminal APPFM in human Alzheimer's disease.
Specific for the C-terminus aa339-348 of human APPFM. IHC titers: labels dystrophic neurites in senile plaques; in formalin fixed paraffinsections @ 1:300 and shows immunoreactivity with neurons containing the APPFM protein.
Neat serum, no preservatives
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP.