APOER2 / LRP8

low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Binds the endoplasmic reticulum resident receptor-associated protein (RAP). Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature. Highly expressed in the initial segment of the epididymis, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), two proteins required for sperm maturation. May also function as an endocytic receptor.

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Products

Antibodies (49)

Proteins (8)

ELISA Kits (5)

Type

Custom (1)

Over-Expression Lysate (4)

Primary (49)

Recombinant (4)

Sandwich (4)

Target

APOER2 / LRP8 (62)

Reactivity

Human (50)

Mouse (15)

Rat (5)

Bovine (5)

Chicken (7)

Dog (3)

Guinea pig (3)

Horse (3)

Application

IHC (21)

IHC-P (15)

WB (46)

Flo (2)

ELISA (16)

ICC (5)

IF (7)

Peptide-ELISA (2)

Host

rabbit (46)

mouse (3)

Product Group

IHCPlus (3)

Isotype

IgG (20)

IgG1 (2)

IgG1,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (46)

Clone

1A1 (1)

6F6B6 (1)

7G12E2 (1)

Format

96-Well Strip Plate (5)

APC (1)

APC Conjugated (2)

Biotin Conjugated (7)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

DY488 Conjugated (2)

DY550 Conjugated (2)

DY650 Conjugated (2)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (2)

Unconjugated (20)

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Epitope

C-Terminus (9)

aa696-941 (8)

aa934-963 (7)

aa395-444 (4)

aa650-699 (4)

420-500 aa, Internal (1)

Internal (1)

aa441-490 (1)

aa500-545 (1)

aa800-900 (1)

aa863-963 (1)

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Publications

No (61)

Yes (1)

Sample Type

Plasma (4)

Serum (4)

Tissue Homogenates (1)

Tag

GST, N-terminus (1)

His (1)

His-GST (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Low Endotoxin Level

Low endotoxin level (1)

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IHC-plus™ APOER2 / LRP8 Antibody (aa863-963) LS-B169

(5.0) Rating

(1) Publication(s)

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa863-963) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$460

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APOER2 / LRP8 Antibody (C-Terminus, Biotin) LS-C140938

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Chicken, Mouse, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

0.1 ml/$416

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APOER2 / LRP8 Antibody (C-Terminus, DY650) LS-C140939

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (C-Terminus) (DY650) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

DY650 Conjugated

Price:

0.1 ml/$416

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APOER2 / LRP8 Antibody (C-Terminus, DY488) LS-C140940

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (C-Terminus) (DY488) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

DY488 Conjugated

Price:

0.1 ml/$416

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APOER2 / LRP8 Antibody (C-Terminus, DY550) LS-C140942

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (C-Terminus) (DY550) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

DY550 Conjugated

Price:

0.1 ml/$416

• Unconjugated
• Biotin
• DY650
• DY488
• DY550

• Unconjugated
• Biotin
• DY650
• More...
  • DY488
  • DY550

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IHC-plus™ APOER2 / LRP8 Antibody (aa800-900) LS-B170

(4.0) Rating

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa800-900) Antibody

Reactivity:

Chicken, Bovine, Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$460

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APOER2 / LRP8 Antibody (aa395-444) LS-B5784

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa395-444) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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APOER2 / LRP8 Antibody (aa395-444, Biotin) LS-C446938

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa395-444) (Biotin) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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APOER2 / LRP8 Antibody (aa395-444, FITC) LS-C446939

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa395-444) (FITC) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

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APOER2 / LRP8 Antibody (clone 6F6B6) LS-C828354

Antibody:

APOER2 / LRP8 Mouse anti-Human Monoclonal (6F6B6) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µg/$459

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APOER2 / LRP8 Antibody LS-C500926

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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APOER2 / LRP8 Antibody (Biotin) LS-C500922

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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APOER2 / LRP8 Antibody (420-500 aa, Internal) LS-C382070

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (420-500 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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Human APOER2 / LRP8 Protein (Recombinant His-GST) (aa696-941) - LS-G15168

Source:

E. coli

Tag:

His-GST

Molecular Weight:

59.3 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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APOER2 / LRP8 Antibody LS-C805662

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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APOER2 / LRP8 Antibody (aa934-963) LS-C100409

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa934-963) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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APOER2 / LRP8 Antibody (aa441-490) LS-C292150

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa441-490) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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APOER2 / LRP8 Antibody (aa500-545) LS-C313670

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa500-545) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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Mouse APOER2 / LRP8 (Sandwich ELISA) ELISA Kit - LS-F15529

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human APOER2 / LRP8 (Sandwich ELISA) ELISA Kit - LS-F13302

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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APOER2 / LRP8 Antibody (clone 7G12E2) LS-C828355

Antibody:

APOER2 / LRP8 Mouse anti-Human Monoclonal (7G12E2) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µg/$459

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Human APOER2 / LRP8 Protein (Recombinant His) (aa52-153) - LS-G141083

Source:

E. coli

Sequence Length:

101 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

11.22 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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APOER2 / LRP8 Antibody (aa934-963) LS-C330337

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa934-963) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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APOER2 / LRP8 Antibody (aa934-963, APC) LS-C275193

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa934-963) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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APOER2 / LRP8 Antibody (aa934-963, PE) LS-C275196

Antibody:

APOER2 / LRP8 Rabbit anti-Human Polyclonal (aa934-963) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• APC
• PE

• Unconjugated
• APC
• PE

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